Results 151 to 160 of about 3,071,774 (310)

Office of Intercultural Student Engagement (ISE) Bookmark

, 2019
Bookmark promoting RISD Office of Intercultural Student Engagement (ISE).
Office, Intercultural Student Engagement
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Consumer Brand Engagement in Social Media: Conceptualization, Scale Development and Validation

, 2014
L. Hollebeek, M. Glynn, R. Brodie
semanticscholar   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Through Their Eyes: Using Photovoice to Capture the Capacity‐Building Journey of Long Covid Patient Experts

Health Expectations
Background Long Covid, characterised by persistent symptoms following the coronavirus disease 2019 (COVID‐19) infection, significantly impacts the quality of life.
Nabil Natafgi, Katie Parris, Erin Walker, Tracey Gartner, Jeanette Coffin, Ariana Mitcham, Luis Sanchez Ferrer, Maushmi K. Patel, Haley Wymbs, Ann Blair Kennedy   +9 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Playful Civic Learning: Enabling Lateral Trust and Reflection in Game-based Public Participation

International Journal of Communication, 2014
Attempts to improve participation in civic life often focus on increasing the number of citizens engaged rather than improving the quality of engagement. As digital interventions flood the civic space, investigating the mediating interfaces that provide
Eric Gordon, Jessica Baldwin-Philippi
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Customer Engagement Behavior: Theoretical Foundations and Research Directions

, 2010
J. van Doorn, Katherine N. Lemon, Vikas Mittal, Stephany Nass, Doréen Pick, Peter Pirner, P. Verhoef   +6 more
semanticscholar   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source