Results 61 to 70 of about 16,770 (180)

Cholesterol Functionalized Nanoparticles Are Effective against Helicobacter pylori, the Gastric Bug: A Proof‐of‐Concept Study

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
Helicobacter pylori gastric infection is widespread and recurrency is common, fuelled by bacterial resistance to antibiotics. Therefore, specific and noninducing resistance alternative treatments are an urgent need. Taking advantage of this gastric pathogen auxotrophy for cholesterol, a “trojan horse” strategy for H.
Ana Sofia Pinho, Renato Pereira, Mariana Pereira, Akhilesh Rai, Lino Ferreira, Maria Cristina Lopes Martins, Paula Parreira   +6 more
wiley   +1 more source

Neuro‐Immunomodulatory Potential of Nanoenabled 4D Bioprinted Microtissue for Cartilage Tissue Engineering

Advanced Healthcare Materials, Volume 14, Issue 5, February 18, 2025.
4D‐bioprinted HCM nanoenabled with ibuprofen‐PLGA nanoparticles is presented. In an in vitro inflamed environment, nanoenabled HCM reduced IL‐1β and IL‐6 release and maintained ECM production, and in vivo, its secretome reduced dendritic cell recruitment, and inflammatory mediators, with no impact on nerve sprouting, indicating neuro‐immunomodulatory ...
Marina Couto, Daniela Pereira Vasconcelos, Catarina Leite Pereira, Estrela Neto, Bruno Sarmento, Meriem Lamghari   +5 more
wiley   +1 more source

Sensor sem fios para monitorização da temperatura intra-corporal [PDF]

, 2012
A aplicação de novas contribuições científicas para a análise de processos fisiológicos deu origem a uma nova era na medicina, introduzindo técnicas e dispositivos para medição e monitorização de parâmetros fisiológicos.
Caldeira, J.M.L.P., Mendes, Américo C., Moutinho, José A. F., Rodrigues, Joel J. P. C.   +3 more
core  

Embedding Bioprinting of Low Viscous, Photopolymerizable Blood‐Based Bioinks in a Crystal Self‐Healing Transparent Supporting Bath

Small Methods, Volume 9, Issue 1, January 20, 2025.
Crystal self‐healing embedding bioprinting (CLADDING) enables the use of low viscosity protein‐based hydrogels as bioinks. By printing liquid bioinks within a transparent, self‐healing support bath governed by complex coacervation, CLADDING allows for the creation of stable, high‐density cellular constructs with excellent viability.
Monize Caiado Decarli, Helena P. Ferreira, Rita Sobreiro‐Almeida, Filipa C. Teixeira, Tiago R. Correia, Joanna Babilotte, Jos Olijve, Catarina A. Custódio, Inês C. Gonçalves, Carlos Mota, João F. Mano, Lorenzo Moroni   +11 more
wiley   +1 more source

Futebol: o estado do conhecimento das dissertações e teses nas engenharias

Revista Brasileira de Futsal e Futebol, 2021
Com objetivo de investigar o estado do conhecimento das dissertações e teses produzidas no Brasil sobre temática futebol nas Engenharias de 1989 a 2018, a pesquisa buscou, recuperou e preparou os dados, dando-lhes tratamento estatí­stico, representação ...
Alex Fensterseifer
doaj  

Characterization of clinical patterns of dengue patients using an unsupervised machine learning approach

BMC Infectious Diseases, 2019
Background Despite the greater sensitivity of the new dengue clinical classification proposed by the World Health Organization (WHO) in 2009, there is a need for a better definition of warning signs and clinical progression of dengue cases.
Gleicy Macedo Hair, Flávio Fonseca Nobre, Patrícia Brasil   +2 more
doaj   +1 more source

Incêndio - um risco constante com elevado potencial de perigo [PDF]

, 2014
Desde a idade média, quando ardiam cidades inteiras, a humanidade tem aprendido muito e tem desenvolvido constantes esforços para evitar e circunscrever os incêndios. Estes esforços, no entanto, foram compensados pelo surgir de outras fontes de ignição e
Rosa, Frederico Miguel Cardoso
core   +2 more sources

Patient‐Derived Melanoma Immune‐Tumoroids as a Platform for Precise High throughput Drug Screening

Advanced Science, Volume 11, Issue 48, December 26, 2024.
Patient‐derived melanoma immune‐tumoroids are developed, consisting of tumor cells, keratinocytes, fibroblasts, and monocytes. These 300 µm MCTs replicate tumor architecture and behavior, closely resembling in vivo tumors. Their secretome panel demonstrate their immune reassembly capacity.
Juliana Viegas, Sofia Costa, Sofia Dias, Catarina Leite Pereira, Bruno Sarmento   +4 more
wiley   +1 more source

Tunable Hybrid Hydrogels of Alginate and Cell‐Derived dECM to Study the Impact of Matrix Alterations on Epithelial‐to‐Mesenchymal Transition

Advanced Healthcare Materials, Volume 13, Issue 29, November 22, 2024.
This study introduces a novel 3D model to explore how ECM properties impact EMT in breast cancer. By combining mechanically‐tunable alginate hydrogels with tumoral‐like decellularized ECM (adECM), the platform successfully recreates key aspects of the TME.
P. Barros da Silva, Xiaoyu Zhao, Sílvia J. Bidarra, Diana S. Nascimento, Vernon LaLone, Bianca N. Lourenço, Joana Paredes, Molly M. Stevens, C. C. Barrias   +8 more
wiley   +1 more source

Artificial intelligence on breast cancer risk prediction

Societal Impacts
Breast Cancer is currently the most commonly diagnosed type of cancer worldwide. While the impacts of this disease can be mitigated through early diagnosis, generalized screening programs based on full-field digital mammography present several ...
João Mendes, Bernardo Oliveira, Carolina Araújo, Joana Galrão, Nuno C. Garcia, Nuno Matela   +5 more
doaj   +1 more source