Enabling genome editing in tropical maize lines through an improved, morphogenic regulator-assisted transformation protocol [PDF]
The recalcitrance exhibited by many maize (Zea mays) genotypes to traditional genetic transformation protocols poses a significant challenge to the large-scale application of genome editing (GE) in this major crop species.
José Hernandes-Lopes +32 more
doaj +2 more sources
Lysine α-ketoglutarate reductase as a therapeutic target for saccharopine pathway related diseases [PDF]
The saccharopine pathway (SacPath) and the pipecolate pathway (PipPath) catabolize lysine to α-aminoadipate. Although the PipPath has been highlighted as the prominent route operating in the brain, recent work has demonstrated that the SacPath plays a ...
Gabriel Vieira Valderrama +6 more
doaj +2 more sources
Identification of electron transfer enzymes in Thermoanaerobacterium saccharolyticum [PDF]
Thermoanaerobacterium saccharolyticum is a promising candidate for the production of biofuels from lignocellulosic sugars; however, the genes associated with electron transfer from ferredoxin are poorly characterized. In this work, we deleted several key
João H. T. M. Fabri +4 more
doaj +2 more sources
Genetic investigation of hydrogenases in Thermoanaerobacterium thermosaccharolyticum suggests that redox balance via hydrogen cycling enables high ethanol yield [PDF]
Thermoanaerobacterium thermosaccharolyticum is an anaerobic and thermophilic bacterium that has been genetically engineered for ethanol production at very high yields.
Layse C. de Souza +2 more
doaj +2 more sources
Can a Top Predator Persist After One of the World's Largest Mining Dam Failures? Occupancy Dynamics of the Neotropical Otter in Brazil's Paraopeba River. [PDF]
We evaluated the effects of the 2019 Brumadinho tailings‐dam collapse on neotropical otters (Lontra longicaudis) in Brazil's Paraopeba river using multi‐season occupancy models. Six years post‐collapse, otters showed high occupancy across impacted reaches.
Massara RL +10 more
europepmc +2 more sources
Genetic Parameter Estimation for Pregnancy Loss and Their Association With Reproductive and Growth Traits in Brahman Cattle Under Extensive Tropical Conditions. [PDF]
ABSTRACT This study estimated genetic parameters for pregnancy loss (PL) in Brahman cattle and evaluated the genetic correlation of PL with growth and reproductive traits using both the pedigree relationship matrix (A) and pedigree plus genomic relationship matrix (H). Data were collected from two herds in Bolivia, focusing on three age groups: heifers,
Cardona-Cifuentes D +7 more
europepmc +2 more sources
Soil Microbiome of Tropical Seasonal and Permanent Small Wetlands. [PDF]
Distinct hydrological regimes shape microbial communities and metabolic pathways in tropical wetlands. Redox‐driven shifts highlight enhanced methanogenesis under anoxia, and dominant archaeal and bacterial groups reflect specific redox conditions and adaptations, with important implications for biogeochemical cycling and climate‐relevant processes ...
Luko-Sulato K +9 more
europepmc +2 more sources
First Assembly of a Draft Genome of the Critically Endangered Northern Muriqui (<i>Brachyteles hypoxanthus</i>, Primates, Atelidae) Including Non-Invasive Genotyping Strategies for the Species. [PDF]
First draft genome assembly of the critically endangered primate northern muriqui (Brachyteles hypoxanthus) and complete mitochondrial genome assembly. Set of microsatellite markers developed for the species for genotyping‐by‐sequencing using high‐throughput sequencing technology and aiming to amplify non‐invasive sampling for population genetics ...
de Melo-Ximenes AA +11 more
europepmc +2 more sources
Analysis of Aspergillus spp. Isolates According to Temporal-Spatial, Sociodemographic, and Clinical Variables-Microsatellite Typing of Clinical and Environmental Samples of Aspergillus fumigatus in a University Hospital in Sao Paulo, Brazil. [PDF]
ABSTRACT Background Typing Aspergillus species is crucial for understanding the sources of infection in hospital environments. Objectives This study analysed clinical and air samples as well as their relationship with the clinical forms of aspergillosis.
Fonseca CA +18 more
europepmc +2 more sources
Bioética e eugenia: pressupostos biopolíticos da manipulação genética
A partir da hipótese de que seres humanos modificados terão projetos de vida bem sucedidos, reflete-se quais seriam os pressupostos biopolíticos da manipulação genética na sociedade moderna. Considerando as teorias apresentadas por Michel Foucault (2005)
Luis Fernando Biasoli +2 more
doaj +1 more source

