Results 41 to 50 of about 5,521,904 (294)

Dedicated Exposure Control for Remote Photoplethysmography

open access: yesIEEE Access, 2020
This paper aims to show that control of exposure time during video capture will improve the accuracy of remote photoplethysmography (rPPG). We propose a purpose specific exposure control algorithm for use in heart rate estimation via rPPG applicable for ...
Jordan Laurie   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

G-quartet driven adaptive hydrogels that integrate constitutional dynamics for antibacterial action and tissue repair

open access: yesiScience
Summary: We report a nucleic acid inspired constitutional dynamic hydrogel (G4TZ) self-assembled from guanosine, a phenylboronic acid, and a thiazole peptide through dynamic covalent linkages formed by boronate ester and imine bonds, together with ...
Sudeshna Mondal   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A review on the auxetic materials and their applications in biomedical engineering

open access: yesSmart Materials in Medicine
Over the past decade, auxetic materials have garnered significant attention due to their unconventional mechanical characteristics. Researchers have proposed multitudinous auxetic materials with improved mechanical properties by designing their core ...
Qiang Gao, Yang Zhou, Zhou Li
doaj   +1 more source

Static structural analysis of different stem designs used in total hip arthroplasty using finite element method

open access: yesHeliyon, 2019
Background: The Hip joint is the primary joint which gives stability to the human body. The wear and tear associated with age and other factors, require these joints to be replaced by implants using hip arthroplasty surgeries. Cobalt chromium alloy (CoCr)
Chethan K.N.   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Responsive hydrogel microfibers for biomedical engineering

open access: yesSmart Medicine, 2022
Responsive hydrogel microfibers can realize multiple controllable changes in shapes or properties under the stimulation of the surrounding environment, and are called as intelligent biomaterials.
Jiahui Guo   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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