Results 111 to 120 of about 1,132,786 (309)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Modern Mechanical Engineering (MME) is an international journal dedicated to the latest advancement of mechanical engineering. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and ...
UBERTINI, FRANCESCO
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Mechanical Engineering 2018 Annual Report
, 2018 A comprehensive look at the Virginia Tech Department of Mechanical Engineering and its accomplishments in ...
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Recent Patents on Mechanical Engineering
Recent Patents on Mechanical Engineering publishes review and research articles, and guest edited thematic issues on recent patents in the field of mechanical engineering.
NOBILE, LUCIO
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, 2010 Examination and practice in the application of many mechanical design elements, including control components. Students working in groups design, fabricate, and test prototype devices in response to requests from industrial sponsors.
Smith, Amy, Frey, Daniel
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Mechanical engineering building, 1951
, 1951 Old mechanical engineering building (formerly the mess hall) on the Norwich University campus in 1951.After the completion of White Hall, Norwich University's mechanical engineering department occupied the former mess hall until the construction of Cabot
Burnham, George H., 1909-1985;
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source