Results 131 to 140 of about 1,132,786 (309)

Modeling the performance of the piston ring-pack in internal combustion engines

open access: yes, 1997
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1997.Includes bibliographical references (leaves 186-194).by Tian Tian.Ph ...
Tian, Tian (Scientist in Mechanical Engineering)
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CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Mechanical Engineering 2016 Annual Report

open access: yes, 2016
The 2016 Annual Report for the Dept. of Mechanical Engineering at Virginia Tech. This issue contains demographic information, a faculty list and a partial list of laboratories within the ME ...

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Mechanical and Aerospace Engineering (MAE) Home [PDF]

open access: yes, 2014
Mechanical and Aerospace Engineering Department at the Naval Postgraduate School website homepage.Web page capture on this date: 2014-05 ...

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Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Mechanical Engineering Shops - 1

open access: yes, 2009
Mechanical Engineering Shopsphotograph date ...
Unknown
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Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Internet for mechanical engineering

open access: yes, 2011
Internet for mechanical engineering is a tutorial from the Virtual Training Suite. The Virtual Training Suite tutorials aim to help university and college students to develop Internet research skills to assist with their coursework and assignments.
Mike Claxton, Fenella Philpot
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Women in Mechanical Engineering: Representation Trends in Education and the Workforce

open access: yes
While percentages of women employed in STEM fields in the United States have generally risen, albeit slowly, over the past several decades, the percentages of women employed in engineering fields specifically has increased at a glacial and stagnating ...
Violi, Angela   +2 more
core   +1 more source

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