Results 41 to 50 of about 13,015,703 (339)
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Managing design variety, process variety and engineering change: a case study of two capital good firms [PDF]
Many capital good firms deliver products that are not strictly one-off, but instead share a certain degree of similarity with other deliveries. In the delivery of the product, they aim to balance stability and variety in their product design and ...
Alblas, A., Veldman, J.
core +5 more sources
Introduction to automatic control systems mathematical background mathematical models of systems classical time-domain analysis of control systems state-space analysis of control systems stability the root locus method frequency domain analysis classical
P. Paraskevopoulos
semanticscholar +1 more source
Learning requirements engineering within an engineering ethos [PDF]
An interest in educating software developers within an engineering ethos may not align well with the characteristics of the discipline, nor address the underlying concerns of software practitioners.
Armarego, J.
core +1 more source
Finite element procedures in engineering analysis
Keywords: Methode des elements finis ; Mathematique ; Elements finis Reference Record created on 2004-09-07, modified on 2016-08 ...
K. Bathe, H. Saunders
semanticscholar +1 more source
Systematic Mapping Studies in Software Engineering
BACKGROUND: A software engineering systematic map is a defined method to build a classification scheme and structure a software engineering field of interest. The analysis of results focuses on frequencies of publications for categories within the scheme.
K. Petersen+3 more
semanticscholar +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling+4 more
wiley +1 more source
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria+3 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source