Results 51 to 60 of about 13,015,703 (339)
Engineering News, Fall 2019 [PDF]
https://scholarcommons.scu.edu/eng_news/1043/thumbnail ...
School of Engineering
core +3 more sources
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
Aspects of the Requirements of ISO 15263.4 and the Design and Development of Bicycle Racks [PDF]
There is currently interest in developing safety standards for bicycle racks for cars. A draft international standard (ISO 15263.4) has been developed. However, there have been many objections to the proposals and a redraft has been made.
Pendle Engineering, Robson, Martin
core
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen+2 more
wiley +1 more source
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter+8 more
wiley +1 more source
Public Perceptions of the Midwest’s Pavements - Wisconsin - Phase I (Winter Ride) [PDF]
The Wisconsin Winter Ride Survey was designed to determine the extent to which drivers were tolerant of the rougher ride of pavements on rural two-lane highways in the winter.
Marquette University,Department of Civil, Construction, and Environmental Engineering
core +1 more source
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker+8 more
wiley +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász+6 more
wiley +1 more source
Engineering at San Jose State University, Spring 2018 [PDF]
https://scholarworks.sjsu.edu/engr_news/1017/thumbnail ...
San Jose State University, Charles W. Davidson College of Engineering
core +2 more sources