Results 51 to 60 of about 10,519,206 (319)

Improved Cuckoo Search (ICS) algorthm for constrained optimization problems

open access: yesLatin American Journal of Solids and Structures
Constrained optimization is very important issue in engineering design. The problem of constrained optimization contains the objective function with linear and nonlinear constraint equations.
Radovan R. Bulatović   +3 more
doaj   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

An overview: the impact of data mining applications on various sectors

open access: yesTehnički Glasnik, 2017
In recent years, it has become difficult to reach to the reliable information with increasing complicated, non-significant, unclear, large and raw data.
Mümine Kaya Keleş
doaj  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Keyword Search Engine Enriched by Expert System Features [PDF]

open access: yesarXiv, 2020
Keyword search engines are essential elements of large information spaces. The largest information space is the Web, and keyword search engines play crucial role there. The advent of keyword search engines has provided a quantum leap in the development of the Web.
arxiv  

The Framework For The Discipline Of Software Engineering in Connection to Information Technology Discipline [PDF]

open access: yesarXiv, 2022
This paper represents preliminary work in identifying the foundation for the discipline of Software Engineering and discovering the links between the domains of Software Engineering and Information Technology (IT). Our research utilized IEEE Transactions on Software Engineering (IEEE-TSE), ACM Transactions on Software Engineering and Methodology (ACM ...
arxiv  

A Targetron-Recombinase System for Large-Scale Genome Engineering of Clostridia

open access: yesmSphere, 2019
Clostridia are a group of Gram-positive anaerobic bacteria of medical and industrial importance for which limited genetic methods are available. Here, we demonstrate an approach to make large genomic deletions and insertions in the model Clostridium ...
Tristan Cerisy   +5 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

A Formal Method for Mapping Software Engineering Practices to Essence [PDF]

open access: yesInternational Journal of Software Engineering,2018,6,9, 2018
Essence Framework EF aims at addressing the core problems of software engineering SE and its ...
arxiv  

Artificial Intelligence Impact On The Labour Force -- Searching For The Analytical Skills Of The Future Software Engineers [PDF]

open access: yesarXiv, 2023
This systematic literature review aims to investigate the impact of artificial intelligence (AI) on the labour force in software engineering, with a particular focus on the skills needed for future software engineers, the impact of AI on the demand for software engineering skills, and the future of work for software engineers.
arxiv  

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