Results 41 to 50 of about 5,939,495 (207)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A versatile force: the future of Australia's special operations capability [PDF]

open access: yes, 2014
This study aims to provide an understanding of the Australian Defence Force\u27s special operations capability and what it offers to government in both peace and wartime.
Benjamin Schreer   +2 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Report on the activities of the Allied Works Council for the period July 1, 1943 to February 15, 1945.

open access: yes, 1945
Cover title: Allied Works Council : report for the period July 1, 1943-February 15, 1915.; Electronic reproduction. Canberra, A.C.T. National Library of Australia, 2010.Allied Works Council : report for the period July 1, 1943-February 15 ...
Allied Works Council (Australia)
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Report on the activities of the Allied Works Council for the period February 26, 1942 to June 30, 1943.

open access: yes, 1943
Cover title: Allied Works Council: report for the period February 26, 1942-June 30, 1943 : secret.; Electronic reproduction. Canberra, A.C.T. : National Library of Australia, 2010.Allied Works Council : report for the period February 26, 1942-June 30 ...
Allied Works Council (Australia)
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Plan of Gyger Gymnasium Renovations, Main Street, Cumberland, Maine, 1965 [PDF]

open access: yes, 1965
Plan of Gyger Gymnasium Renovations, Main Street, Cumberland, Maine was created by Allied Engineering Incorporated in 1965.
Allied Engineering Incorporated
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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