Results 71 to 80 of about 6,337,766 (219)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

N8197 v. 1 no. 5.

open access: yes, 2020
Mediterranean Allied Tactical Air Force, an operational component of Mediterranean Allied Air Forces, was an integrated command composed mainly of United States Army Air Force (Twelfth Air Force) and Royal Air Force (Desert Air Force) units.
Mediterranean Allied Tactical Air Force
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Resilience Engineering and Integrated Operations in the Petroleum Industry [PDF]

open access: yes, 2010
This white paper provides an overview of Resilience Engineering and seeks to answer the following questions: • What is Resilience Engineering? • Why do we need Resilience Engineering in integrated operations?
Tveiten, Camilla K.   +2 more
core  

Operations instructions no. 52: Allied Air Forces.

open access: yes, 2022
Central Pacific forces continue the offensive by seizing Stevedore, Tattersalls, and Tearaway in order to establish air and naval facilities thereon. The Allied Air Forces cover and support the offensive of the Central Pacific forces.
Headquarters, Allied Air Forces, Southwest Pacific Area; Beebe, R. E.
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Operations instructions no. 69: Allied Air Forces.

open access: yes, 2022
The Allied Air Forces were to extend daily long range overwater reconnaissance in the western Celebes Sea, Sulu Sea, and along the coast of the eastern Philippines.
Headquarters, Allied Air Forces, Southwest Pacific Area; Beebe, R. E.
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Managing complexity: challenges for industrial engineering and operations management

open access: yes, 2014
This book presents papers by experts in the field of Industrial Engineering, covering topics in business strategy; modelling and simulation in operations research; logistics and production; service systems; innovation and knowledge; and project ...
López-Paredes, Adolfo   +2 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

History of M.A.A.F., 1 September 1944 - 9 May 1945.

open access: yes, 2007
This narrative comprises Part II of the history of the Mediterranean Allied Air Forces. It covers the eight months from September 1, 1944 until the end of the European war on 8 May 1945. Continued from Part I, chapters 12-18 include military operations,
Headquarters Mediterranean Allied Air Forces
core  

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