Results 101 to 110 of about 4,725,711 (307)
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley+2 more
wiley +1 more source
A Principal-Agent Model of Systems Engineering Processes with Application to Satellite Design [PDF]
We present a principal-agent model of a one-shot, shallow, systems engineering process. The process is one-shot in the sense that decisions are made during one time step and that they are final. The term shallow refers to a one-layer hierarchy of the process.
arxiv
The mathematical components of engineering expertise: the relationship between doing and understanding mathematics [PDF]
this paper are extracts from our interviews with engineers.) Where, then, is the complex mathematics that certainly exists in modern engineering? Throughout all aspects of engineering design, computer software has an overwhelming presence.
Kent, Phillip, Noss, Richard
core +2 more sources
The interaction between Agrobacterium fabrum phytochromes Agp1 and Agp2 was studied using FRET. Full‐length and truncated proteins with varied label positions provided spatial insights, narrowing down from many docking models to three. These models explain Agp2's reduction in Agp1 autophosphorylation, with Arg83 of Agp2 specifically evolved to interact
Afaf El Kurdi+7 more
wiley +1 more source
Deep & Cross Network for Ad Click Predictions
Feature engineering has been the key to the success of many prediction models. However, the process is non-trivial and often requires manual feature engineering or exhaustive searching.
Fu, Bin+3 more
core +1 more source
Algorithm Engineering for All-Pairs Suffix-Prefix Matching [PDF]
All-pairs suffix-prefix matching is an important part of DNA sequence assembly where it is the most time-consuming part of the whole assembly. Although there are algorithms for all-pairs suffix-prefix matching which are optimal in the asymptotic time ...
Lim, Jihyuk, Park, Kunsoo
core +1 more source
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri+8 more
wiley +1 more source
Engineering - young people want to be informed [PDF]
Young people in developed nations recognise the contribution that science and technology make to society and acknowledge their importance now and in the future, yet few view their study as leading to interesting careers.
Bryce, C.+7 more
core
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten+10 more
wiley +1 more source
Optimizing the placement of new wells and well spacing are vital issues in oilfield development. In recent years, the use of particle swarm algorithm (PSA) in many reservoir applications has gained wide acceptance.
Evans Annan Boah+3 more
doaj +1 more source