Results 101 to 110 of about 4,725,711 (307)

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, Volume 599, Issue 8, Page 1113-1121, April 2025.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

A Principal-Agent Model of Systems Engineering Processes with Application to Satellite Design [PDF]

open access: yesarXiv, 2019
We present a principal-agent model of a one-shot, shallow, systems engineering process. The process is one-shot in the sense that decisions are made during one time step and that they are final. The term shallow refers to a one-layer hierarchy of the process.
arxiv  

The mathematical components of engineering expertise: the relationship between doing and understanding mathematics [PDF]

open access: yes, 2002
this paper are extracts from our interviews with engineers.) Where, then, is the complex mathematics that certainly exists in modern engineering? Throughout all aspects of engineering design, computer software has an overwhelming presence.
Kent, Phillip, Noss, Richard
core   +2 more sources

Interaction between bacterial phytochromes Agp1 and Agp2 of Agrobacterium fabrum by fluorescence resonance energy transfer and docking studies

open access: yesFEBS Letters, Volume 599, Issue 6, Page 848-865, March 2025.
The interaction between Agrobacterium fabrum phytochromes Agp1 and Agp2 was studied using FRET. Full‐length and truncated proteins with varied label positions provided spatial insights, narrowing down from many docking models to three. These models explain Agp2's reduction in Agp1 autophosphorylation, with Arg83 of Agp2 specifically evolved to interact
Afaf El Kurdi   +7 more
wiley   +1 more source

Deep & Cross Network for Ad Click Predictions

open access: yes, 2017
Feature engineering has been the key to the success of many prediction models. However, the process is non-trivial and often requires manual feature engineering or exhaustive searching.
Fu, Bin   +3 more
core   +1 more source

Algorithm Engineering for All-Pairs Suffix-Prefix Matching [PDF]

open access: yes, 2017
All-pairs suffix-prefix matching is an important part of DNA sequence assembly where it is the most time-consuming part of the whole assembly. Although there are algorithms for all-pairs suffix-prefix matching which are optimal in the asymptotic time ...
Lim, Jihyuk, Park, Kunsoo
core   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, Volume 599, Issue 8, Page 1159-1168, April 2025.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

Engineering - young people want to be informed [PDF]

open access: yes, 2010
Young people in developed nations recognise the contribution that science and technology make to society and acknowledge their importance now and in the future, yet few view their study as leading to interesting careers.
Bryce, C.   +7 more
core  

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, Volume 599, Issue 9, Page 1317-1336, May 2025.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

Critical evaluation of infill well placement and optimization of well spacing using the particle swarm algorithm

open access: yesJournal of Petroleum Exploration and Production Technology, 2019
Optimizing the placement of new wells and well spacing are vital issues in oilfield development. In recent years, the use of particle swarm algorithm (PSA) in many reservoir applications has gained wide acceptance.
Evans Annan Boah   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy