Results 81 to 90 of about 1,989,992 (317)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Engineering News

open access: yes, 2015
In fall 2011, ground was broken for the Signature Engineering Building, a dream project of current engineering Dean Richard C. Benson and Virginia Tech President Emeritus and former College of Engineering Dean Paul Torgersen.
Nystrom, Lynn   +2 more
core  

Superharmonic proton motion in high-energy-density organic electrodes for aqueous zinc batteries

open access: yesNature Communications
The limited proton transfer kinetics within organic positive electrodes restricts the proton storage capacity and hinders achieving high energy density in aqueous zinc-organic batteries.
Boyu Li   +11 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Modern Engineering : Science and Education

open access: yes, 2016
This book draws together the most interesting recent results to emerge in mechanical engineering in Russia, providing a fascinating overview of the state of the art in the field in that country which will be of interest to a wide readership.
Evgrafov, Alexander
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Does Engineering need Technological Literacy? Does Technological Literacy Need Engineering?

open access: yes, 2022
Background: This paper reviews a pedagogical journey teaching Technological Literacy classes for over ten years in Colleges of Engineering and of Design. Technological literacy programs face challenges in our institutions.
Mina, Mani
core  

Accounting of infiltration waters and the level of recharge of the root layer by groundwater when calculating the irrigation regime on drained lands [PDF]

open access: yesBIO Web of Conferences
The paper provides a justification for the need to take into account the inflow of infiltration waters into the soil profile and groundwater recharge when calculating the irrigation regime of agricultural crops. The studies were performed on sod-podzolic
Mazhaysky Yuri, Pavlov Artyom
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

21st International Conference on Industrial Engineering and Engineering Management

open access: yes, 2015
Being the premier forum for the presentation of new advances and research results in the fields of Industrial Engineering, IEEM 2014 aims to provide a high-level international forum for experts, scholars and entrepreneurs at home and abroad to present ...
Shen, Jiang, Dou, Runliang, Qi, Ershi
core   +1 more source

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