Results 151 to 160 of about 25,235,368 (365)

Active learning increases student performance in science, engineering, and mathematics

Proceedings of the National Academy of Sciences of the United States of America, 2014
S. Freeman, Sarah L. Eddy, Miles McDonough, Michelle K. Smith, Nnadozie Okoroafor, Hannah Jordt, M. Wenderoth   +6 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Journal of Materials Engineering and Performance Celebrates Its 30th Anniversary!

Journal of materials engineering and performance (Print), 2022
R. Asthana, W. Frazier
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Inorganic All‐Solid‐State Sodium Batteries: Electrolyte Designing and Interface Engineering [PDF]

, 2023
Yaxiong Yang, Shoumeng Yang, Xu Xue, Xianghua Zhang, Qifei Li, Yu Yao, Xianhong Rui, Hongge Pan, Yan Yu   +8 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Interface engineering for silicon/carbon composite anode in all-solid-state batteries

Energy Materials and Devices
Silicon-based anode is a promising candidate for all-solid-state batteries (ASSBs). However, it must be further improved because of its tremendous volume change.
Xiang Gao, Linan Jia, Xi Zhang
doaj   +1 more source

Argument-driven Engineering in Middle School Science Classrooms: The Study of Engineering Attitudes and Efforts to Broaden Engineering Participation by Exposing All Students to Multiple Engineering Design Tasks (RTP, Diversity) [PDF]

, 2020
Lawrence Chu, Victor Sampson, Todd L. Hutner, Stephanie Rivale, Richard Crawford, Christina Baze, Hannah Brooks   +6 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

THE STRUCTURE OF YIELD OF RICE BREEDING SAMPLES AND ITS EFFECT ON PRODUCTIVITY

Зерновое хозяйство России, 2018
The article gives the results of the structural analysis of the productivity of rice breeding samples from control seed-plot during the years of 2012-2014.
P. I. Kostylev, Е. V. Krasnova, A. А. Redkin, L. М. Kostylevа, A. V. Aksenova   +4 more
doaj   +2 more sources