Engineering strategies to overcome the current roadblocks in CAR T cell therapy
Nature Reviews Clinical Oncology, 2019 T cells genetically engineered to express chimeric antigen receptors (CARs) have proven — and impressive — therapeutic activity in patients with certain subtypes of B cell leukaemia or lymphoma, with promising efficacy also demonstrated in patients with ...
S. Rafiq +2 more
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Improvement of agrotechnics of cultivation of table carrot in the conditions of the Volgograd region
Овощи России, 2020 Relevance. The Volgograd region is one of the major producing regions of table carrots with a difficult climate, therefore, regional adaptation of technology parameters and optimization of reclamation regimes under drip irrigation is necessary. According
B. M. Kizyaev +2 more
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Craniotomy Simulator with Force Myography and Machine Learning-Based Skills Assessment
Bioengineering, 2023 Craniotomy is a fundamental component of neurosurgery that involves the removal of the skull bone flap. Simulation-based training of craniotomy is an efficient method to develop competent skills outside the operating room.
Ramandeep Singh +3 more
doaj +1 more source
System engineering approach applied to Galileo system [PDF]
, 2010 Developing a localization system, with more precise performances than GPS that guarantees Europe autonomy is a complex challenge that ESA and a large number of European economical actors of space industry were decided to meet.
Bouchired, Steven +1 more
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Heat-resistant concrete based on alumina cement from substandard raw material [PDF]
, 2011 Results are provided for development of refractory concrete based on modified alumina cement using chemical industry waste. A quantitative ratio for mixed filler fractions, the effect of production factors on concrete strength, the dependence of its ...
de Arnaldo Araujo, A. +3 more
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“MOR” engineering of antibodies in ALL [PDF]
Blood, 2017 In this issue of Blood , Schewe and colleagues identify a novel Fc-engineered CD19 antibody with significant activity in a xenograft model of patient-derived mixed lineage leukemia ( MLL )–rearranged acute lymphoblastic leukemia (ALL ...
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Performance of Carboxymethyl Cellulose Produced from Cocoa Pod Husk as Fluid Loss Control Agent at High Temperatures and Variable (Low and High) Differential Pressure Conditions-Part 1 [PDF]
Journal of Petroleum Science and Technology, 2019 Environmental concerns and cost associated with drilling operations have made us promote the application of biodegradable and renewable drilling fluid additives, particularly at high temperature.
Wilberforce Aggrey +4 more
doaj +1 more source
Personalized 3D Printed Eye Gear for Microscopic Surgeons Amidst and beyond COVID-19
Bioengineering, 2023 The COVID-19 pandemic underscored the need for enhanced protective measures for healthcare workers, particularly surgeons, who face a heightened risk of exposure to infectious aerosols. However, conventional eye protection equipment such as face shields,
Ramandeep Singh +2 more
doaj +1 more source
What Should Conceptual Engineering Be All About? [PDF]
Philosophia, 2021 AbstractConceptual engineering is commonly characterized as the method for assessing and improving our representational devices. Little has been said, however, on how best to construe these representational devices—in other words, on what conceptual engineering should be all about.
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Engineering the multiscale complexity of vascular networks
Nature Reviews Materials, 2022 The survival of vertebrate organisms depends on highly regulated delivery of oxygen and nutrients through vascular networks that pervade nearly all tissues in the body.
Colleen E. O’Connor +4 more
semanticscholar +1 more source