Results 31 to 40 of about 3,088,866 (298)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Engineering: good for technology education? [PDF]

open access: yes, 2011
Recent curriculum changes in the educational system of Australia have resulted in study options being available in Engineering for senior secondary students to use for university entrance.
Williams, P. John
core  

Science, Engineering and Technology for Better Future

open access: yesInternational Journal of Technology, 2020
The current need to reduce dependence on non-renewable fuels has contributed a lot to the rapid growth of renewable energy systems and electric vehicles. One of the exciting sources of energy storage is the battery.
Eny Kusrini   +13 more
doaj   +1 more source

Technology transfer: software engineering and engineering design [PDF]

open access: yesComputing & Control Engineering Journal, 1992
Software engineering has made significant contributions to “engineering-in-the-large”. The nature of the software process has been researched, and computer based tools and environments have been built to support this process. Other more established engineering disciplines, such as instrument design, have developed professional practices, mature ...
Finkelstein, A.   +3 more
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Technology-Conversant Management Education: Introducing A New Discipline

open access: yesSouth African Journal of Industrial Engineering, 2014
In the first quarter of 2013, the Department of Industrial Engineering at the University of Stellenbosch launched a new academic course, Strategic Technology Analysis (STA), as an elective in its M.Sc. in Engineering Management and M.Eng.
Van Wyk, Rias Johann
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

An engineering design knowledge reuse methodology using process modelling [PDF]

open access: yes, 2007
This paper describes an approach for reusing engineering design knowledge. Many previous design knowledge reuse systems focus exclusively on geometrical data, which is often not applicable in early design stages.
Young, Bob   +9 more
core   +1 more source

State science, engineering, and technology program, Georgia

open access: yes, 1978
Issued as Quarterly reports no. 1-4, Financial statement, and Final report, Project no.
Aton, Carol Lynn
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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