Results 41 to 50 of about 1,825,876 (215)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Innovation Promoted by Meta-Engineering - Mining-Exploring-Converging-Implementing Process [PDF]
Journal of Systemics, Cybernetics and Informatics, 2012 The authors propose a new creative concept of “metaengineering” as a dynamic engineering approach that is effective for breakthrough innovation. A science and technology driven country is expected to play a leading role in addressing increasingly more ...
Hiroshi Suzuki, Yuji Okita
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Review of deterministic networking technology
Dianxin kexue, 2023 Deterministic networking was proposed to meet the demands of high bandwidth, low delay and high reliability for audio and video, industrial control, power protection and other applications.With the development of new services such as virtual/augmented ...
Xiaodong DUAN +4 more
doaj +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Double ESOs-based field-oriented control for PMSM drive system with current sensorless
Journal of Measurement Science and Instrumentation, 2019 A novel double extended state observers（ESOs）-based field-oriented control（FOC） strategy is developed for three-phase permanent magnet synchronous motor（PMSM） drive systems without any phase current sensor. In principle, two current sensors are essential
TENG Qing-fang +5 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
آموزش مهندسی ایران, 2020 Purpose: The present study aims to compare the specialization of Tehran Universities of Technology in the field of engineering. Material and methods: In this applied and scientometric study, data of Tehran Universities of Technology was collected using ...
Erfan Ghaderi azad +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source