Results 61 to 70 of about 5,500,511 (357)
Experimental study on stability and rheological properties of aqueous foam in the presence of reservoir natural solid particles [PDF]
, 2016 The authors would like to acknowledge the school of engineering at the University of Aberdeen and University Technology Malaysia (UTM) to provide required materials and facilities to complete this research.Peer ...
Hamidi, Hossein +2 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Preparing Low-Skilled Workers for the Jobs of Tomorrow [PDF]
, 2008 Identifies ways for state policies to leverage technology-based economic development by preparing low-skilled workers for middle-skill, technical jobs in the fields of science, technology, engineering, and math (STEM).
Kenneth E. Poole
core
Synovial joint lubrication – does nature teach more effective engineering lubrication strategies? [PDF]
, 2007 Nature shows numerous examples of systems which show energy efficiency, elegance in their design and optimum use of materials. Biomimetics is an emerging field of research in engineering and successes have been documented in the diverse fields of ...
Liskiewicz, T. +3 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
STEM: Science, Technology, Engineering and Math [PDF]
, 2013 Science is on our minds at Linfield. Students and faculty spent the summer collaborating on research in the sciences, mathematics and technology, both here and ...
Davis, Laura, Mileham, Mardi
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Research on management and application of tunnel engineering based on BIM technology
Journal of Civil Engineering and Management, 2019 The emergence of BIM technology has provided powerful technical means for realizing informatization and digitization in the field of engineering construction, which remarkably promotes the transformation and advance of production and management modes in ...
ZhanPing Song +5 more
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source