Results 161 to 170 of about 4,649,067 (302)

Comparative analysis of AI and expert evaluations in engineering design pedagogy. [PDF]

PLoS One
Coşkun TK, Altan EB.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

A memorized multi-objective Sinh-Cosh optimizer for solving multi-objective engineering design problems. [PDF]

Sci Rep
El-Nagar D, Zeidan I, Issa M.
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

An adaptive multi-scale kriging framework with committee-based infill for engineering design optimization. [PDF]

Sci Rep
Xie H, Zhong Q, Zeng W.
europepmc   +1 more source

Innovations in Remote Teaching of Engineering Design Teams. [PDF]

Annu Conf Expo (Am Soc Eng Educ), 2023
Kang S, Blakeney EA, Yasuhara K, Kearney KE, Payne S, Seibel E, Liu JTC, Reinhall P, Posner J.   +8 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Correction: An axiomatic system engineering design method based on NSGA-II algorithm applied to complex systems. [PDF]

Sci Rep
Zhang X, Zhang Q, Zhao Q, Zhao S, Zhao Y, Guo Y, Zhao Z, Song L.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A Generative AI Framework for Cognitive Intervention in Older Adults: An Integrated Engineering Design and Clinical Protocol. [PDF]

Healthcare (Basel)
Jeong T, Hwang G, Kim DY.
europepmc   +1 more source