Results 1 to 10 of about 1,734,815 (167)

Prognostic model to identify and quantify risk factors for mortality among hospitalised patients with COVID-19 in the USA

BMJ Open, 2021
Objectives To develop a prognostic model to identify and quantify risk factors for mortality among patients admitted to the hospital with COVID-19.Design Retrospective cohort study.
Shemra Rizzo, Xiao Li, Devin Incerti, Lisa Lindsay, Vincent Yau, Dan Keebler, Jenny Chia, Larry Tsai   +7 more
doaj   +1 more source

Estimation of the allelic status of apolipoprotein E4 isoforms with fully automated LUMIPULSE® assays

Exploration of Neuroscience, 2023
Aim: Apolipoprotein E (ApoE) isoforms, especially the ApoE4 isoform, are genetic risk factors for Alzheimer’s disease (AD). Moreover, the APOE ε4 haplotype has a dose-dependent association with an increased risk of amyloid-related imaging abnormalities ...
Tatsushi Yuri, Rosina Degrieck, Dagmara Minczakiewicz, Hideo Sato, Jo Kamada, Takuya Nakazawa, Ina Vandenbroucke, Katsumi Aoyagi, Hisashi Nojima   +8 more
doaj   +1 more source

The SPACE of developer productivity [PDF]

Communications of the ACM, 2021
There's more to it than you think.
Nicole Forsgren, Margaret-Anne D. Storey, Chandra Shekhar Maddila, Thomas Zimmermann 0001, Brian Houck, Jenna L. Butler   +5 more
openaire   +1 more source

Biodistribution of the saponin-based adjuvant Matrix-M™ following intramuscular injection in mice

Frontiers in Drug Delivery, 2023
Novel adjuvants are extensively utilized in the development of safe and effective vaccines against emerging pathogens. Matrix-M™ adjuvant is a saponin-based adjuvant used in several active clinical development programs and in widespread use in the COVID ...
Cecilia Carnrot, Berit Carow, Anna-Karin E. Palm, Eray Akpinar, Per-Henrik Helgesson, Ingrid Lekberg Osterman, Emelie Bringeland, Bryant Foreman, Nita Patel, Johan Bankefors, Louis Fries, Linda Stertman   +11 more
doaj   +1 more source

Evaluation of water quality index and geochemical characteristics of surfacewater from Tawang India

Scientific Reports, 2022
In this study,the water samples were collected from 31 sites of Tawang, Arunachal Pradesh, India (North-Eastern Himalaya), during the winter season to check the suitability of water for drinking and irrigation purposes.The study scientifically ...
Nisha Gaur, Arpan Sarkar, Dhiraj Dutta, B. J. Gogoi, Rama Dubey, Sanjai Kumar Dwivedi   +5 more
doaj   +1 more source

Pick and place process for uniform shrinking of 3D printed micro- and nano-architected materials

Nature Communications, 2023
Two-photon polymerization lithography is promising for producing three-dimensional structures with user-defined micro- and nanoscale features. Additionally, shrinkage by thermolysis can readily shorten the lattice constant of three-dimensional photonic ...
Tomohiro Mori, Hao Wang, Wang Zhang, Chern Chia Ser, Deepshikha Arora, Cheng-Feng Pan, Hao Li, Jiabin Niu, M. A. Rahman, Takeshi Mori, Hideyuki Koishi, Joel K. W. Yang   +11 more
doaj   +1 more source

High throughput screening data for a case study of CHO cell culture process development

Data in Brief, 2021
In this article, we present four sets of data from high-throughput screening (HTS) studies of different chemically defined media using an industrially relevant Chinese hamster ovary (CHO) cell line.
Qin He, Jianlin Xu, Erik Vandermark, Jun Tian, Yueming Qian, Cynthia Chelius, Jongchan Lee, Michael C. Borys, Zheng Jian Li, Girish Pendse   +9 more
doaj   +1 more source

Productive Ecosystems and the arrow of development [PDF]

Nature Communications, 2021
AbstractEconomic growth is associated with the diversification of economic activities, which can be observed via the evolution of product export baskets. Exporting a new product is dependent on having, and acquiring, a specific set of capabilities, making the diversification process path-dependent.
Neave O’Clery, Muhammed Ali Yıldırım, Ricardo Hausmann   +2 more
openaire   +8 more sources

Development of an intensified fed-batch production platform with doubled titers using N-1 perfusion seed for cell culture manufacturing

Bioresources and Bioprocessing, 2020
The goal of cell culture process intensification is to increase volumetric productivity, generally by increasing viable cell density (VCD), cell specific productivity or production bioreactor utilization in manufacturing.
Jianlin Xu, Matthew S. Rehmann, Mengmeng Xu, Shun Zheng, Charles Hill, Qin He, Michael C. Borys, Zheng Jian Li   +7 more
doaj   +1 more source

N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing

Bioengineering, 2022
Fed-batch process intensification with a significantly shorter culture duration or higher titer for monoclonal antibody (mAb) production by Chinese hamster ovary (CHO) cells can be achieved by implementing perfusion operation at the N-1 stage for ...
Emily S. C. Rittershaus, Matthew S. Rehmann, Jianlin Xu, Qin He, Charles Hill, Jeffrey Swanberg, Michael C. Borys, Zheng-Jian Li, Anurag Khetan   +8 more
doaj   +1 more source