Results 11 to 20 of about 6,360,422 (309)

Deadlines in Product Development [PDF]

open access: yesSSRN Electronic Journal, 2012
Deadlines are common in product development and are often felt to be too harsh—many development efforts are still worth continuing at the time of mandated termination. We examine the value of deadlines from the agency-theoretic perspective. We consider a firm that pays an agent to lead product development activities.
Zhang, Juanjuan
openaire   +6 more sources

Productivity Developments Abroad [PDF]

open access: yesFederal Reserve Bulletin, 2000
This article reviews recent productivity trends in foreign industrial countries. The focus of the analysis is on whether productivity abroad has accelerated to an extent comparable to that observed in the United States. The authors find that foreign labor productivity, unlike that of the United States, has not accelerated in the latter half of the ...
Christopher J. Gust, Jaime R. Marquez
openaire   +1 more source

Upstream cell culture process characterization and in-process control strategy development at pandemic speed

open access: yesmAbs, 2022
As of early 2022, the coronavirus disease 2019 (COVID-19) pandemic remains a substantial global health concern. Different treatments for COVID-19, such as anti-COVID-19 neutralizing monoclonal antibodies (mAbs), have been developed under tight timelines.
Jianlin Xu   +4 more
doaj   +1 more source

Product Development vs. Production Development

open access: yesProcedia CIRP, 2014
AbstractThe lifecycle of a product and the lifecycle of the respective production equipment intersect in the production phase of the product, which at the same time represents the use phase of the production equipment. Product development and production development however follow more or less independent pathways, making use of different terminology ...
Vielhaber, Michael, Stoffels, Pascal
openaire   +1 more source

Developments on Product Propagation [PDF]

open access: yes, 2014
Product Propagation (pp) is an algorithm to backup probabilistic evaluations for abstract two-player games. It was shown that pp could solve Go problems as efficiently as Proof Number Search (pns). In this paper, we exhibit three domains where, for generic non-optimized versions, pp performs better (see the nuances in the paper) than previously known ...
Abdallah Saffidine, Tristan Cazenave
openaire   +1 more source

Ranking mAb–excipient interactions in biologics formulations by NMR spectroscopy and computational approaches

open access: yesmAbs, 2023
Excipients are added to biopharmaceutical formulations to enhance protein stability and enable the development of robust formulations with acceptable physicochemical properties, but the mechanism by which they confer stability is not fully understood ...
Chunting Zhang   +11 more
doaj   +1 more source

Disease progression modeling of the North Star Ambulatory Assessment for Duchenne Muscular Dystrophy

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2023
Duchenne muscular dystrophy (DMD) is a rare genetic disorder caused by decreased or absent dystrophin gene leading to progressive muscle degeneration and weakness in young boys.
Jennifer E. Hibma   +3 more
doaj   +1 more source

Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction

open access: yesmAbs, 2021
Monoclonal antibody (mAb) interchain disulfide bond reduction can cause a loss of function and negatively impact the therapeutic’s efficacy and safety.
Seo-Young Park   +9 more
doaj   +1 more source

Requirements for Automotive LiDAR Systems

open access: yesSensors, 2022
Light detection and ranging (LiDAR) are fundamental sensors that help driving tasks for autonomous driving at various levels. Commercially available systems come in different specialized design schemes and involve plenty of specifications.
Zhuoqun Dai   +5 more
doaj   +1 more source

Effective Virtual Teams for New Product Development [PDF]

open access: yes, 2012
At present, the existing literature shows that the factors which influence the effectiveness of virtual teams for new product development are still ambiguous.
Abdul Rashid, Salwa Hanim   +3 more
core   +7 more sources

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