Results 11 to 20 of about 1,788,691 (267)
Productivity Developments Abroad [PDF]
Federal Reserve Bulletin, 2000 This article reviews recent productivity trends in foreign industrial countries. The focus of the analysis is on whether productivity abroad has accelerated to an extent comparable to that observed in the United States. The authors find that foreign labor productivity, unlike that of the United States, has not accelerated in the latter half of the ...
Christopher J. Gust, Jaime R. Marquez
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N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing
Bioengineering, 2022 Fed-batch process intensification with a significantly shorter culture duration or higher titer for monoclonal antibody (mAb) production by Chinese hamster ovary (CHO) cells can be achieved by implementing perfusion operation at the N-1 stage for ...
Emily S. C. Rittershaus +8 more
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Developments on Product Propagation [PDF]
, 2014 Product Propagation (pp) is an algorithm to backup probabilistic evaluations for abstract two-player games. It was shown that pp could solve Go problems as efficiently as Proof Number Search (pns). In this paper, we exhibit three domains where, for generic non-optimized versions, pp performs better (see the nuances in the paper) than previously known ...
Abdallah Saffidine, Tristan Cazenave
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mAbs, 2023 Excipients are added to biopharmaceutical formulations to enhance protein stability and enable the development of robust formulations with acceptable physicochemical properties, but the mechanism by which they confer stability is not fully understood ...
Chunting Zhang +11 more
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Design Automation for Complex Optical Systems [PDF]
EPJ Web of ConferencesThis paper introduces a constraint-based workflow for the unbiased development of optical systems, addressing the growing complexity of modern optical design.
Wohletz Jona +4 more
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mAbs, 2021 Monoclonal antibody (mAb) interchain disulfide bond reduction can cause a loss of function and negatively impact the therapeutic’s efficacy and safety.
Seo-Young Park +9 more
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Disease progression modeling of the North Star Ambulatory Assessment for Duchenne Muscular Dystrophy
CPT: Pharmacometrics & Systems Pharmacology, 2023 Duchenne muscular dystrophy (DMD) is a rare genetic disorder caused by decreased or absent dystrophin gene leading to progressive muscle degeneration and weakness in young boys.
Jennifer E. Hibma +3 more
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mAbs, 2022 As of early 2022, the coronavirus disease 2019 (COVID-19) pandemic remains a substantial global health concern. Different treatments for COVID-19, such as anti-COVID-19 neutralizing monoclonal antibodies (mAbs), have been developed under tight timelines.
Jianlin Xu +4 more
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Deadlines in Product Development [PDF]
SSRN Electronic Journal, 2012 Deadlines are common in product development and are often felt to be too harsh—many development efforts are still worth continuing at the time of mandated termination. We examine the value of deadlines from the agency-theoretic perspective. We consider a firm that pays an agent to lead product development activities.
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Alzheimer’s Research & Therapy, 2019 Background We previously investigated low doses (105 or 225 mg) of gantenerumab, a fully human monoclonal antibody that binds and removes aggregated amyloid-β by Fc receptor-mediated phagocytosis, in the SCarlet RoAD (SR) and Marguerite RoAD (MR) phase 3
Gregory Klein +13 more
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