FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Innovation Inspired by Nature: Applications of Biomimicry in Engineering Design. [PDF]
Biomimetics (Basel)Aguilar-Planet T, Peralta E.
europepmc +1 more source
Engineering Design of High-Efficiency Multi-Purpose Nuclear Electric Power Systems
, 2013 버하누딘
openalex +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Towards a Novel Digital Twin Framework Proposal Within the Engineering Design Process for Future Engineers: An IoT Smart Building Use Case. [PDF]
Sensors (Basel)Boltsi A +4 more
europepmc +1 more source
Induced Partial Saturation: From Mechanical Principles to Engineering Design of an Innovative and Eco-Friendly Countermeasure against Earthquake-Induced Soil Liquefaction [PDF]
Lucia Mele +2 more
openalex +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Improved marine predators algorithm for engineering design optimization problems. [PDF]
Sci RepChun Y, Hua X, Qi C, Yao YX.
europepmc +1 more source
From collaborative design to efficient engineering of optimized products based on knowledge
, 2012 Antoine Varret +2 more
openalex +1 more source