Results 71 to 80 of about 4,404,417 (294)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
EnergiesThis review provides a comprehensive analysis of advanced control strategies and operational optimization of energy systems, focusing on heat pumps, with an emphasis on their role in enhancing energy efficiency and operational flexibility.
Konstantinos Sittas +2 more
doaj +1 more source
Metals, 2019 Shrinkage porosities and non-metallic inclusions are common manufacturing process based defects that are present within cast materials. Conventional fatigue design recommendations, such as the FKM guideline (“Forschungskuratorium Maschinenbau”
Manuel Schuscha +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The engineering design process as a problem solving and learning tool in K-12 classrooms
, 2013 Paper ID #7971 The engineering design process as a problem solving and learning tool in K- 12 classrooms Jennifer Mangold, University of California, Berkeley Ph.D. candidate at UC-Berkeley, Mangold studies in the mechanical engineering department.
Jennifer Mangold, S. Robinson
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
SeparationsCentrifugal Partition Chromatography (CPC) is a separation technique that utilizes immiscible liquid phases to purify compounds. The selection of solvents in Liquid–Liquid Chromatography offers flexibility and optimization possibilities for specific ...
Felix Buthmann +4 more
doaj +1 more source
Design-engineering relation in yacht design process
IDA: International Design and Art Journal, 2021 Depending on the developing technology, the increase in the options of yacht production methods and materials has gained an important role not only sizewise but also in the increase of variety of yachts.
Bülent İbrahim Turan
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applied SciencesRapeseed press cake (RPC), the protein-rich residue from edible oil production, is currently underutilized and is primarily used as animal feed. This study aimed to investigate pressurized liquid extraction (PLE) for protein recovery from RPC using ...
Christoforos Vasileiou +4 more
doaj +1 more source