Results 31 to 40 of about 91,694 (238)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Study on the Method of Automatically Drawing Multiscale Engineering Geotechnical (Geological) Sections Step by Step of Engineering Layers including Lenses

Advances in Civil Engineering, 2022
Drawing the engineering sections automatically and efficiently is significant for the investigation results of geotechnical engineering to provide the scientific and detailed geological basis for urban planning and construction, but it is still difficult
Guangjun Ji, Nannan Zhao, Xiaoyuan Zhou, Qian Wang, Yan Lu, Zizhao Cai   +5 more
doaj   +1 more source

A Review of Neural Network Approach on Engineering Drawing Recognition and Future Directions

JOIV: International Journal on Informatics Visualization, 2023
Engineering Drawing (ED) digitization is a crucial aspect of modern industrial processes, enabling efficient data management and facilitating automation. However, the accurate detection and recognition of ED elements pose significant challenges.
Muhammad Syukri Mohd Yazed, Ezak Fadzrin Ahmad Shaubari, Moi Hoon Yap   +2 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

A comparative study on teaching methods of engineering drawing course 1

آموزش مهندسی ایران, 2012
According to the modeling software and computer technology, teaching engineering graphics courses in Iranian universities must be improved similar to other top universities in the world which have changed since 2000.
Mehdi Mottaghipour
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

PECULIARITIES OF USING THE METHODOLOGY DISTANCE LEARNING OF THE SUBJECT «ENGINEERING AND COMPUTER GRAPHICS» FOR STUDENTS STUDYING BY CORRESPONDENCE

Інформаційні технології і засоби навчання, 2010
A great part of the distance course of the subject «Engineering and Computer Graphics» (ECG) placed in Internet looks as an electronic manual. But the distance training process has a complicated structure and combines not only studying theoretical ...
Olena V. Slobodianiuk
doaj  

The technical development of architectural drawing in modern China

Frontiers of Architectural Research, 2014
Western architectural drawing techniques were introduced to China in the 1870s, when their importance was increasingly recognized by the Chinese. The development of architectural drawing in the nation led to the dissemination of knowledge on engineering ...
Keming Liu
doaj   +1 more source