Results 41 to 50 of about 5,671,099 (295)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Інформаційні технології і засоби навчання, 2010 A great part of the distance course of the subject «Engineering and Computer Graphics» (ECG) placed in Internet looks as an electronic manual. But the distance training process has a complicated structure and combines not only studying theoretical ...
Olena V. Slobodianiuk
doaj
A comparative study on teaching methods of engineering drawing course 1
آموزش مهندسی ایران, 2012 According to the modeling software and computer technology, teaching engineering graphics courses in Iranian universities must be improved similar to other top universities in the world which have changed since 2000.
Mehdi Mottaghipour
doaj +1 more source
Gong-kuang zidonghua, 2022 The coal resources in Xinjiang are shallowly buried, the coal seam is thick, resulting in poor top coal caving and drawing. And the roof is overhanging in a large area, which makes it impossible to achieve safe and efficient top coal mining.
SUN Qiang +6 more
doaj +1 more source
Perfecting engineering and technical drawing: reducing errors and misinterpretations
, 2015 This concise reference helps readers avoid the most commonplace errors in generating or interpreting engineering drawings. Applicable across multiple disciplines, Hanifan’s lucid treatment of such essential skills as understanding and conveying data in a
Hanifan, Ron
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Digital Chemical Engineering, 2022 The design and engineering of piping and instrumentation diagrams (P&ID) is a very time-consuming and labor-intensive process. Although P&IDs show common patterns that could be reused during development, the drawing is usually created manually and built ...
Jonas Oeing +5 more
doaj +1 more source
Automatically Drawing Euler Diagrams with Circles [PDF]
, 2012 Euler diagrams are used for visualizing categorized data. These categories, together with information about when categories share some datum, can be turned into a succinct diagram description from which an Euler diagram can be generated.
Howse, John +3 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source