Results 41 to 50 of about 871,677 (295)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Using artificial intelligence to support the drawing of piping and instrumentation diagrams using DEXPI standard

Digital Chemical Engineering, 2022
The design and engineering of piping and instrumentation diagrams (P&ID) is a very time-consuming and labor-intensive process. Although P&IDs show common patterns that could be reused during development, the drawing is usually created manually and built ...
Jonas Oeing, Wolfgang Welscher, Niclas Krink, Lars Jansen, Fabian Henke, Norbert Kockmann   +5 more
doaj   +1 more source

STUDI RELEVANSI MATERI MATA KULIAH GAMBAR TEKNIK DAN MATERI MATA PELAJARAN PRODUKTIF SMK PROGRAM KEAHLIAN GAMBAR TEKNIK DENGAN MATERI STANDAR UJI KOMPETENSI [PDF]

, 2014
Gambar Teknik sebagai bagian dari ilmu dalam bidang keteknikan, yang dipelajari baik oleh SMK teknologi salah satunya program Keahlian Gambar Teknik, maupun dalam perkuliahan khususnya di Departemen Pendidikan Teknik Mesin FPTK UPI, meskipun sama-sama ...
Hamdan, -
core  

Identification of Local Lubrication Regimes on Textured Surfaces by 3D Roughness Curvature Radius [PDF]

, 2014
This paper proposes a new method of 3D roughness peaks curvature radius calculation and its application to tribological contact analysis as a characteristic signature of tribological contact.
Bigerelle, Maxence, Dubar, Laurent, Hubert, Cedric, Kubiak, Krzysztof   +3 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Study on the Method of Automatically Drawing Multiscale Engineering Geotechnical (Geological) Sections Step by Step of Engineering Layers including Lenses

Advances in Civil Engineering, 2022
Drawing the engineering sections automatically and efficiently is significant for the investigation results of geotechnical engineering to provide the scientific and detailed geological basis for urban planning and construction, but it is still difficult
Guangjun Ji, Nannan Zhao, Xiaoyuan Zhou, Qian Wang, Yan Lu, Zizhao Cai   +5 more
doaj   +1 more source

A Review of Neural Network Approach on Engineering Drawing Recognition and Future Directions

JOIV: International Journal on Informatics Visualization, 2023
Engineering Drawing (ED) digitization is a crucial aspect of modern industrial processes, enabling efficient data management and facilitating automation. However, the accurate detection and recognition of ED elements pose significant challenges.
Muhammad Syukri Mohd Yazed, Ezak Fadzrin Ahmad Shaubari, Moi Hoon Yap   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Survey of University Engineering Departments in the State of Washington to Determine Engineering Drawing Requirements for High Schools [PDF]

, 1962
It was the purpose of this study to determine (1) whether a course in engineering drawing designed to parallel part of the first year engineering college drawing requirement could be taught in the high schools in the state of Washington and (2) how much ...
Brousseau, James E.
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source