Results 111 to 120 of about 8,852,576 (377)
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
ENGINEERING EDUCATION: PRACTICE-ORIENTED APPROACH
The paper substantiates the need to strengthen the practical orientation of engineering education in modern socio-economic conditions. The paper shows that introduction of context-related tasks during classroom hours correspond to the implementation of ...
N. N. Dvulichanskaya, V. B. Piasetsky
doaj
Revision of engineering education for 21st century
What knowledge, skills, and attitudes should students have upon graduation? And how can we ascertain that they have acquired these capabilities? These have been fundamental questions in engineering education during the last two decades.
H. Memarian
doaj +1 more source
Digital Twin (DT) technology is an essential technology related to the Industry 4.0. In engineering education, it is important that the curricula are kept up-to-date.
Antti Liljaniemi, Heikki Paavilainen
semanticscholar +1 more source
Walking Through the Method Zoo: Does Higher Education Really Meet Software Industry Demands? [PDF]
Software engineering educators are continually challenged by rapidly evolving concepts, technologies, and industry demands. Due to the omnipresence of software in a digitalized society, higher education institutions (HEIs) have to educate the students ...
Conte, T.+7 more
core +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
The importance of understanding computer analyses in civil engineering [PDF]
Sophisticated computer modelling systems are widely used in civil engineering analysis. This paper takes examples from structural engineering, environmental engineering, flood management and geotechnical engineering to illustrate the need for civil ...
Borthwick, Alistair+4 more
core +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
A review of literature on communication skills development (CSD) in the engineering curriculum [PDF]
Engineering education has expanded recently to include emphasis on the development of some very specific non-technical attributes that match a strong technical base to produce well-rounded engineering graduates who are flexible and adaptable to suit the ...
Awang, Zubaidah, Othman, Rohani
core
The Practices of Play and Informal Learning in the miniGEMS STEAM Camp [PDF]
Science, Technology, Engineering, and Mathematics (STEM) play an important role in the educational reform and global economy. However, STEM education lacks the hands-on laboratory in the formal middle school and high school curricula.
Frye, Michael+2 more
core +1 more source