Results 221 to 230 of about 9,714,306 (345)

Implementation of a Six-Layer Smart Factory Architecture with Special Focus on Transdisciplinary Engineering Education. [PDF]

Sensors (Basel), 2021
Ralph BJ, Sorger M, Schödinger B, Schmölzer HJ, Hartl K, Stockinger M.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The Implementation of 3D Printing in Engineering Education in the Field of Hydraulic and Pneumatic Components. [PDF]

3D Print Addit Manuf
Vukašinović V, Gordić D, Šušteršič V, Josijević M, Nikolić J.   +4 more
europepmc   +1 more source

A Modular Multirotor Unmanned Aerial Vehicle Design Approach for Development of an Engineering Education Platform. [PDF]

Sensors (Basel), 2021
Kotarski D, Piljek P, Pranjić M, Grlj CG, Kasać J.   +4 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Software engineering education in the era of conversational AI: current trends and future directions. [PDF]

Front Artif Intell
Sengul C, Neykova R, Destefanis G.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Research hotspots and development trends of K-12 engineering education research: Bibliometric analysis based on CiteSpace. [PDF]

Heliyon
Jin D, Jian M, Liu S.
europepmc   +1 more source

Using Virtual Reality in Biomedical Engineering Education. [PDF]

J Biomech Eng, 2020
Singh A, Ferry D, Ramakrishnan A, Balasubramanian S.   +3 more
europepmc   +1 more source