Results 41 to 50 of about 2,376,720 (336)

Traditional vocations and modern professions among Tamil Brahmans in colonial and post-colonial south India [PDF]

open access: yes, 2010
Since the nineteenth century, Tamil Brahmans have been very well represented in the educated professions, especially law and administration, medicine, engineering and nowadays, information technology.
Fuller, C. J., Narasimhan, Haripriya
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Innovation in Engineering Educations:Today's Need, Tomorrow's Inevitability

open access: yesآموزش مهندسی ایران, 2009
During the past two decades, socio-economic changes and new technologies have had drastic impacts on higher education in general, and on engineering education in particular.
Abbas Bazargan
doaj   +1 more source

Teaching Software Engineering through Robotics [PDF]

open access: yes, 2014
This paper presents a newly-developed robotics programming course and reports the initial results of software engineering education in robotics context. Robotics programming, as a multidisciplinary course, puts equal emphasis on software engineering and ...
Meyer, Bertrand   +2 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

ENGINEERING EDUCATION IN IRAN

open access: yesآموزش مهندسی ایران
Modern engineering education in Iran has gone through many ups and downs in the 9 decades since its beginning. One of the most recent changes is the unprecedented expansion of engineering education, which began in the 2001s and reached its peak in 2011 ...
Hossein Memarian
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Finite element model updating of a RC building considering seismic response trends [PDF]

open access: yes, 2013
ACKNOWLEDGEMENTS The authors would like to thank their supporters. GeoNet staff, particularly Dr Jim Cousins, Dr S.R. Uma and Dr Ken Gledhill, helped with access to seismic data and building information.
Butt, F., Omenzetter, P.
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Challenges, Strategies and Recommendations for Reengineering Engineering Education in Sub-Saharan Africa: A Review

open access: yesScience, Engineering and Technology, 2023
With the continent of Africa occupying the front seat of underdevelopment in the world, and its population increasing exponentially, there is an urgent need to come up with strategies to tackle the underdevelopment ravaging the continent and the demand ...
Themba Mashiyane   +3 more
doaj   +1 more source

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