Results 41 to 50 of about 2,373,501 (286)

Active learning based laboratory towards engineering education 4.0 [PDF]

open access: yes, 2019
Universities have a relevant and essential key role to ensure knowledge and development of competencies in the current fourth industrial revolution called Industry 4.0.
Delgado Prieto, Miquel   +5 more
core   +1 more source

Innovation in Engineering Educations:Today's Need, Tomorrow's Inevitability

open access: yesآموزش مهندسی ایران, 2009
During the past two decades, socio-economic changes and new technologies have had drastic impacts on higher education in general, and on engineering education in particular.
Abbas Bazargan
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Research and Education in Computational Science and Engineering [PDF]

open access: yes, 2016
Over the past two decades the field of computational science and engineering (CSE) has penetrated both basic and applied research in academia, industry, and laboratories to advance discovery, optimize systems, support decision-makers, and educate the ...
Biros, George   +32 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Creativity in Mass-Education Contexts [PDF]

open access: yes, 2006
This paper discusses a learning framework (working title: ‘fog framework’) that has been developed in response to the challenge of teaching creative subjects in a mass-education context.
Anusas, M.
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Engineering programme structure requirements for Bologna compliance [PDF]

open access: yes, 2007
In 1999 twenty nine European countries have signed the Bologna Declaration to establish a common European higher education system as for the year 2010. Engineering Ireland has decided that the education standard for the title of CEng and MIEI should be ...
Olabi, Abdul-Ghani
core  

ENGINEERING EDUCATION IN IRAN

open access: yesآموزش مهندسی ایران
Modern engineering education in Iran has gone through many ups and downs in the 9 decades since its beginning. One of the most recent changes is the unprecedented expansion of engineering education, which began in the 2001s and reached its peak in 2011 ...
Hossein Memarian
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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