Results 51 to 60 of about 648,638 (314)

The Objectives of Engineering Education [PDF]

open access: yesFanāvarī-i āmūzish, 2012
In developing the models and approaches for engineering education, in addition to having technical knowledge (engineering science) there is a specific focus on skills and attitudes (engineering practice). Hence, the determination of engineering education
H. Motahhari Nejad   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Innovation in Engineering Educations:Today's Need, Tomorrow's Inevitability

open access: yesآموزش مهندسی ایران, 2009
During the past two decades, socio-economic changes and new technologies have had drastic impacts on higher education in general, and on engineering education in particular.
Abbas Bazargan
doaj   +1 more source

Blended learning the higher education classroom : a critical review of developments within engineering education

open access: yes, 2018
The rapid development of technology in the past two decades has had many points of contact and impact upon the global higher education sector. Technology and globalisation have unlocked entirely new directions for higher education and has provided a ...
Afsharian, Azadeh   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

InterdisciplinaryProgramms, Engineering in Higher Education [PDF]

open access: yesInterdisciplinary Studies in the Humanities, 2012
Review and study how and type of planning system of higher education, is considered constant and serious. According to the needs and circumstances ,a variety of ideas, over time, have raised.
Mahbobe Arefi
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

ENGINEERING EDUCATION IN IRAN

open access: yesآموزش مهندسی ایران
Modern engineering education in Iran has gone through many ups and downs in the 9 decades since its beginning. One of the most recent changes is the unprecedented expansion of engineering education, which began in the 2001s and reached its peak in 2011 ...
Hossein Memarian
doaj   +1 more source

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