Results 41 to 50 of about 12,491,947 (302)
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The rapid development of technology in the past two decades has had many points of contact and impact upon the global higher education sector. Technology and globalisation have unlocked entirely new directions for higher education and has provided a ...
Afsharian, Azadeh +2 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
What Every Engineer Should Know about Engineering Education [PDF]
The purpose of this paper is to present the current status of the literature of engineering education. In order to accomplish this task several questions are discussed: Who publishes the documents? What are the topics of the articles published?
Osorio, Nestor L.
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Redefining engineering education: the reflective practice of product design engineering [PDF]
The University of Glasgow and the School of Design at the Glasgow School of Art have joined forces to redefine the nature of an engineering curriculum and produce a degree program that is rich in both creative design culture and design engineering skills.
Green, G.
core +5 more sources
Modern mechanical engineering: research, development and education
This book covers modern subjects of mechanical engineering such as nanomechanics and nanotechnology, mechatronics and robotics, computational mechanics, biomechanics, alternative energies, sustainability as well as all aspects related with mechanical ...
Davim, J. Paulo, editor. +2 more
core +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Innovation in Engineering Educations:Today's Need, Tomorrow's Inevitability
During the past two decades, socio-economic changes and new technologies have had drastic impacts on higher education in general, and on engineering education in particular.
Abbas Bazargan
doaj +1 more source

