Results 71 to 80 of about 9,714,306 (345)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

InterdisciplinaryProgramms, Engineering in Higher Education [PDF]

open access: yesInterdisciplinary Studies in the Humanities, 2012
Review and study how and type of planning system of higher education, is considered constant and serious. According to the needs and circumstances ,a variety of ideas, over time, have raised.
Mahbobe Arefi
doaj   +1 more source

Game-Based Learning in Engineering Education [PDF]

open access: yes, 2008
The new generation of undergraduates entering UK higher education have grown up with computer games of ever increasing sophistication. In this educational project a race game, Racing Academy, was developed to investigate how game technology and gaming ...
Darling, Jos   +4 more
core  

Walking Through the Method Zoo: Does Higher Education Really Meet Software Industry Demands? [PDF]

open access: yes, 2019
Software engineering educators are continually challenged by rapidly evolving concepts, technologies, and industry demands. Due to the omnipresence of software in a digitalized society, higher education institutions (HEIs) have to educate the students ...
Conte, T.   +7 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

ENGINEERING EDUCATION IN IRAN

open access: yesآموزش مهندسی ایران
Modern engineering education in Iran has gone through many ups and downs in the 9 decades since its beginning. One of the most recent changes is the unprecedented expansion of engineering education, which began in the 2001s and reached its peak in 2011 ...
Hossein Memarian
doaj   +1 more source

Creativity in Mass-Education Contexts [PDF]

open access: yes, 2006
This paper discusses a learning framework (working title: ‘fog framework’) that has been developed in response to the challenge of teaching creative subjects in a mass-education context.
Anusas, M.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Engineering Education Periodicals and Proceedings: Increasing Awareness of and Access to the Literature [PDF]

open access: yes, 2002
In the vast realm, of engineering literature there is a set of publications that is often unknown and certainly underutilized: engineering education periodicals and proceedings.
De Petro, Thomas G
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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