Results 81 to 90 of about 12,491,947 (302)
The Application of Artificial Intelligence in Engineering Education: A Systematic Review
IEEE AccessArtificial Intelligence (AI) is increasingly impacting the environment, pedagogy, and management practices in engineering education. However, literature reviews that provide a systematic review and analysis of AI in engineering education remain limited ...
Cong Liu +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2021 All rights reserved.Entrepreneurial learning experiences have become one of the key aspects of the state of the art in engineering education. As such, technology-focused entrepreneurship courses have been incorporated to engineering curricula — both in ...
Hilliger Carrasco, Isabel +4 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Ethics in an engineering curriculum
, 2003 Although Ethics and Engineering have existed as separate academic entities for a long time, it is only comparatively recently that the former formally became a part of the engineering profession and an accepted component of an engineering curriculum ...
Ilic, Vojislav
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A Comprehensive Assessment Plan for Accreditation in Engineering Education: A Case Study in Turkey
, 2015 This paper describes the procedure followed by Computer Engineering and Software Engineering programs at Atilim University, Ankara, Turkey, which led to the granting of five years of accreditation by MUDEK, the local accreditation body authorized by The ...
Şengül, Gökhan +2 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Project-based learning of systems engineering V model with the support of 3D printing [PDF]
27th Australasian Association for Engineering Education Annual Conference - Coffs Harbour, Australia, 4-7 Dec 2016202402 bcchVersion of RecordSelf ...
Tang, YM, Mo, JPT
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