Results 191 to 200 of about 5,632,873 (248)
PCGF1 Promotes the Tumorigenesis of Malignancies Through Upregulating CCDC34 in Glioma
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Polycomb group factor 1 (PCGF1) and coiled‐coil domain‐containing protein 34 (CCDC34) have been implicated in tumorigenesis in multiple malignancies. However, their biological functions and prognostic significance in glioma remain poorly defined.
Yuanbing Chen +7 more
wiley +1 more source
A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham +7 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Blood‐based biomarkers are increasingly used to identify Alzheimer's disease (AD) pathology and may play an important role in early disease screening and participant selection for clinical trials. However, their performance across stages of cognitive impairment remains unclear. This study examined whether plasma biomarkers differ in
Maryam Abdolmaleki +7 more
wiley +1 more source
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Engineering Practice and Engineering Ethics
Science, Technology, & Human Values, 2000Diane Vaughan’s analysis of the causes of the Challenger accident suggests ways to apply science and technology studies to the teaching of engineering ethics. By sensitizing future engineers to the ongoing construction of risk during mundane engineering practice, we can better prepare them to address issues of public health, safety, and welfare before ...
Lynch, W., Kline, R.
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“An Ethics of Commitment for Engineers”
Science and Engineering Ethics, 2022This paper follows a trend in engineering ethics away from universal moral theories towards more contingent/contextual approaches such as pragmatist and care ethics. These methodological considerations are treated in the context of the Volkswagen Diesel Emissions scandal as a case study in the "paradox of loyalty," (i.e.
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Ethics in Biomedical Engineering
2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2008This session focuses on a number of aspects of the subject of Ethics in Biomedical Engineering. The session starts by providing a case study of a company that manufactures artificial heart valves where the valves were failing at an unexpected rate.
Ahmed, Morsy, Jennifer, Flexman
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The Hastings Center Report, 1977
dominated the study of society, more questions of ethics and public policy appear. Policy makers want to know the values woven into technical issues. Sometimes, though, the lists of values seem simply tacked onto the science. There ought to be a field of policy criticism and political criticism that is more in tune with the humanities than the sciences-
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dominated the study of society, more questions of ethics and public policy appear. Policy makers want to know the values woven into technical issues. Sometimes, though, the lists of values seem simply tacked onto the science. There ought to be a field of policy criticism and political criticism that is more in tune with the humanities than the sciences-
openaire +2 more sources
Science and Engineering Ethics, 2008
This paper describes four plays which illustrate ethical themes relevant to engineers and which could be used as a resource for engineers who wish to explore ethical topics and their relationship with professional practice. The plays themselves have been chosen because a character in the play is involved in engineering activities. Each play is analysed
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This paper describes four plays which illustrate ethical themes relevant to engineers and which could be used as a resource for engineers who wish to explore ethical topics and their relationship with professional practice. The plays themselves have been chosen because a character in the play is involved in engineering activities. Each play is analysed
openaire +3 more sources
2007 IEEE International Symposium on Technology and Society, 2007
Ethics, what are ethics and how should one use them in their work and lives? In this context how will ethics be used in relation to engineering and business? In the fields of engineering and business, individuals are guided in their decisions and actions by ethics.
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Ethics, what are ethics and how should one use them in their work and lives? In this context how will ethics be used in relation to engineering and business? In the fields of engineering and business, individuals are guided in their decisions and actions by ethics.
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IEEE Software, 2009
Compliance to a professional society's code of ethics carries obligations beyond minimum standards of behavior. Members of software engineering professional societies should also serve the public interest and promote the common good.
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Compliance to a professional society's code of ethics carries obligations beyond minimum standards of behavior. Members of software engineering professional societies should also serve the public interest and promote the common good.
openaire +2 more sources