Results 171 to 180 of about 795,087 (236)

The Implementation of a Blended Counseling Intervention in Undergraduate Engineering Students: The Effect on Mental Health. [PDF]

Healthcare (Basel)
Kalamatianos A, Kounenou K, Pezirkianidis C.   +2 more
europepmc   +1 more source

Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells remain the industry standard for producing numerous therapeutic proteins, particularly monoclonal antibodies (mAbs). However, achieving higher recombinant protein titers remains an ongoing challenge and a fundamental understanding of the cellular mechanism driving improved bioprocess performance remains ...
Kate E. Meeson, Joanne Watson, Susan Rosser, Ellie Hawke, Andrew Pitt, Tessa Moses, Leon Pybus, Magnus Rattray, Alan J. Dickson, Jean‐Marc Schwartz   +9 more
wiley   +1 more source

Spatiotemporal evolution and the multidimensional proximity mechanism of megaproject innovation networks. [PDF]

PLoS One
He H, Xu L, Huang Y.
europepmc   +1 more source

Physiology and Robustness of Yeasts Exposed to Dynamic pH and Glucose Environments

Biotechnology and Bioengineering, EarlyView.
The authors investigated how three Saccharomyces cerevisiae strains respond to dynamic substrate and pH oscillations using dynamic microfluidic single‐cell cultivation (dMSCC) and intracellular biosensors. By combining performance and robustness analysis of selected intracellular parameters, growth and morphological analysis, the authors identified ...
Luca Torello Pianale, Luisa Blöbaum, Alexander Grünberger, Lisbeth Olsson   +3 more
wiley   +1 more source

Synthesis and Physical-Chemical Characterization of a Biopolymer Derived from Cassava Starch, Cashew Nutshell Liquid, and Diammonium Phosphate. [PDF]

Polymers (Basel)
Humánez MA, Vega YV, Almario AA, Palma Calabokis O, Baldovino JJA.   +4 more
europepmc   +1 more source

Systematic Investigation of Impact of Antifoam and Extracellular Vesicles on Fouling of Hollow Fiber Filters in Intensified Perfusion Processes Highlights the Key Impact of Antifoam

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Ultra‐high cell density perfusion cultures are becoming increasingly attractive for biologics manufacturing due to their ability to boost productivity and offer a flexible manufacturing footprint. However, these intensified perfusion processes pose challenges, particularly concerning the performance of hollow fiber filters used as cell ...
Sri Ranganayaki Madabhushi, Qianying Zuo, Carol Zhou, Chelsea Phuangthong, Nathaniel Ruppert, Tiffany Tang, Francisco Pelaez   +6 more
wiley   +1 more source

Thermal compaction as an alternative approach for full-RAP base layer construction. [PDF]

Sci Rep
Coelho LM, Marchi BZ, da Silveira PHPM, de Azevedo ARG, Monteiro SN, Guimarães ACR.   +5 more
europepmc   +1 more source

Small Intestine on a Chip Demonstrates Physiologic Mucus Secretion in the Presence of Lacticaseibacillus rhamnosus Biofilm

Biotechnology and Bioengineering, EarlyView.
Dash and coworkers have fabricated a small intestine on a chip, which encapsulates the physiology and biofilm of the small intestinal epithelium. The dynamic system showed villus differentiation within 5 days of flow, and the mucus layer and biofilm showed small intestinal characteristics.
Sanat Kumar Dash, Cláudia N. H. Marques, Gretchen J. Mahler   +2 more
wiley   +1 more source

Probabilistic analysis of ground settlement induced by soil and rock composite foundation excavation considering spatial variability. [PDF]

Sci Rep
Zhang Y, Zhang Z, Liu S, Gao M, Wang J, Cao J.   +5 more
europepmc   +1 more source

Electrochemical Catheter Hub Operated by a Wearable Micropotentiostat Prevents Acinetobacter baumannii Infection In Vitro

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Intraluminal infection of central venous catheters, used for long‐term treatment, can result in central line‐associated bloodstream infection (CLABSI). These infections can be challenging to prevent and treat due to formation of biofilms within catheter lumens, which shield bacteria from the human immune response and conventional antimicrobial
Majid Al‐Qurahi, Derek Fleming, Won‐Jun Kim, Ibrahim Bozyel, Robin Patel, Haluk Beyenal   +5 more
wiley   +1 more source