Results 81 to 90 of about 12,057,244 (369)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Editorial: Human decision-making behaviors in engineering and management: A neuropsychological perspective

Frontiers in Neuroscience, 2022
Hanliang Fu, Hanliang Fu, Gui Ye, Gui Ye, Jiayu Chen, Pin-Chao Liao   +5 more
doaj   +1 more source

Integration of Sustainable Development Principles into Engineering Management Practices: Analysing the Impact on Companies’ Efficiency and Competitiveness

Управленческие науки
The article examines the challenges and tasks related to integrating sustainable development principles into production and technological, engineering and technical, as well as managerial and economic processes.
V. S. Novitskii
doaj   +1 more source

Intersubjective management in aerospace engineering

MATEC Web of Conferences, 2017
This article presents a postnonclassical approach to create the science of management processes organization in a developing society, the focus of which is “the man of culture”, i.e.
Arpentieva Mariam, Duvalina Olga, Gorelova Irina   +2 more
doaj   +1 more source

RWU Approves Campus Location for New SECCM Labs [PDF]

, 2017
With Trustees\u27 approval, RWU plans to break ground in spring on School of Engineering, Computing and Construction Management ...
Fitzpatrick, Edward
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

The Environmental Influencing Factors of the Realization of Engineering Construction Harmony from the Perspective of Ren–Shi–Wu: Evidence from China

Buildings
Engineering construction involves many internal factors and external environmental factors, resulting in conflict or uncoordinated problems in engineering management.
Weiwei Zuo, Ning Yan, Qiankun Wang
doaj   +1 more source

Boundary Objects and their Use in Agile Systems Engineering

, 2019
Agile methods are increasingly introduced in automotive companies in the attempt to become more efficient and flexible in the system development. The adoption of agile practices influences communication between stakeholders, but also makes companies ...
Knauss, Eric, Larsson, Mats, Pelliccione, Patrizio, Wohlrab, Rebekka   +3 more
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Methodical Problems in Organic Farming Research [PDF]

, 2002
Workshop presentation with particular focus on values, transferability and praxis relevance of organic farming research. Examples from agricultural engineering lead to the conclusion, that prototype farming, goal oriented project management ...
Schäfer, Winfried
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