Results 61 to 70 of about 585,858 (260)

The Research of the Project Proprietor’ s Management Control of Engineering Change

open access: yesSHS Web of Conferences, 2015
The problem of the engineering budgetary estimate surpass engineering cost estimate, engineering budget surpass engineering budgetary estimate, engineering final accounts surpass engineering budget in our country’s present stage of the engineering ...
Pan Yanhua, Chen Yanfan
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Improving Recruitment and Retention: A Management Framework to Utilize DMAIC and Kaizen for Student Support in Engineering Education

open access: yesTrends in Higher Education
The Clay N. Hixson Student Success Center within the College of Engineering at Tennessee Tech University has undergone a transformative upgrade by integrating the Define, Measure, Analyze, Improve, and Control (DMAIC) framework with select Kaizen ...
Kumar Yelamarthi   +2 more
doaj   +1 more source

ORGANIZATION OF CIVIL ENGINEERING BUSINESS MANAGEMENT SYSTEM BASED ON DIGITAL TECHNOLOGY

open access: yesНаучно-технические ведомости СПбГПУ: Экономические науки, 2020
It is possible to increase effectivity in the civil engineering sector, one of the most important sectors for the Economics of Russian Federation—with digital technologies.
ustinova liliya, Roman Nicolay
doaj   +1 more source

Project management for engineers

open access: yes, 2016
In recent years we have witnessed a rapid growth in the use of project management methods and tools as a means by which organisations achieve their objectives. Projects drive business in industries as diverse as transportation, pharmaceuticals, banking, and hospitals etc.
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Competency requirements for engineering management undergraduates in the era of intelligent construction

open access: yesJournal of Asian Architecture and Building Engineering
In the era of intelligent construction, engineering management requires diverse abilities that cannot be provided through traditional engineering management education.
Dingli Liu   +4 more
doaj   +1 more source

Developing an Effective System for Engineering Management Education: A Teaching Practice and Evaluation Perspective

open access: yesEducation Sciences
In the field of engineering management, teaching emphasizes the cultivation of applied talents within the context of new engineering disciplines. Evaluating the effectiveness of this cultivation is particularly necessary.
Tengfei Zhao   +5 more
doaj   +1 more source

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