Results 51 to 60 of about 593,607 (260)
AIDLC–FMEA: Explainability-Integrated Lifecycle Risk Assessment for AI Governance
IEEE AccessThe growing deployment of AI-enabled systems in safety- and decision-critical contexts has exposed limitations in existing governance and risk assessment approaches, particularly regarding lifecycle alignment, interpretability, and decision support. This
Chin-Pei He, Yu-Ru Pan, Kuo-Chung Chu
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
BuildingsEngineering construction involves many internal factors and external environmental factors, resulting in conflict or uncoordinated problems in engineering management.
Weiwei Zuo, Ning Yan, Qiankun Wang
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Project management for engineers
, 2016 In recent years we have witnessed a rapid growth in the use of project management methods and tools as a means by which organisations achieve their objectives. Projects drive business in industries as diverse as transportation, pharmaceuticals, banking, and hospitals etc.
openaire +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The Research of the Project Proprietor’ s Management Control of Engineering Change
SHS Web of Conferences, 2015 The problem of the engineering budgetary estimate surpass engineering cost estimate, engineering budget surpass engineering budgetary estimate, engineering final accounts surpass engineering budget in our country’s present stage of the engineering ...
Pan Yanhua, Chen Yanfan
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
ORGANIZATION OF CIVIL ENGINEERING BUSINESS MANAGEMENT SYSTEM BASED ON DIGITAL TECHNOLOGY
Научно-технические ведомости СПбГПУ: Экономические науки, 2020 It is possible to increase effectivity in the civil engineering sector, one of the most important sectors for the Economics of Russian Federation—with digital technologies.
ustinova liliya, Roman Nicolay
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