Results 121 to 130 of about 551,729 (311)

The Automatism Capture the Account Parameter in Engineering Figure Using Computer

open access: yes, 2011
This text advance the method of automatism capture the engineering parameter in figure using computer, thread conversion and account the coordinate, capture the engineering parameter in figure, can frank capture the engineering parameter in curve from ...
Qiang Li, Jian Zhong Li
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Research on factor analysis and method for evaluating grouting effects using machine learning

open access: yesScientific Reports
The evaluation of grouting effects constitutes a critical aspect of grouting engineering. With the maturity of the grouting project, the workload and empirical characteristics of grouting effect evaluation are gradually revealed.
Wenxin Li   +4 more
doaj   +1 more source

Parameter Estimation of the Three-Parameter Weibull Distribution Based on an Iterative CDF Method

open access: yesMathematics
Parameter estimation of the three-parameter Weibull distribution is an important problem in reliability analysis and statistical modeling. Random right-censored data are widely encountered in engineering practice.
Shenglei Liu   +4 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Beaver behavior optimizer: A novel metaheuristic algorithm for solar PV parameter identification and engineering problems

open access: yesJournal of Advanced Research
Introduction: Numerical optimization plays a key role in improving the efficiency of solar photovoltaic (PV) systems and solving complex engineering problems.
Kaichen Ouyang   +8 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Development of crow search algorithm using the characteristics of qubits and application of engineering problems

open access: yesScientific Reports
Recently, researchers have attempted to develop a new algorithm by combining quantum systems and metaheuristics algorithms and are confirming its applicability in engineering optimization problems.
Donwoo Lee, Seungjae Lee
doaj   +1 more source

Engineering Parameter Design for CO2 Geological Storage: Research Progress and Case Analyses

open access: yesEng
Carbon Capture and Storage (CCS) is a critical technology for promoting carbon reduction and achieving the carbon neutrality goal. As a vital component of CCS projects, the injection process makes it especially important to clarify wellsite layout ...
Hangyu Liu, Wei Lian, Jun Li, Yanxian Wu
doaj   +1 more source

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