Results 51 to 60 of about 2,429,228 (292)
Holographic heat engine with momentum relaxation [PDF]
Sci. China Phys. Mech. Astron. (2018) 61: 080421, 2017 We investigate the heat engine defined via black hole with momentum relaxation, which is introduced by massless axion fields. We first study the extended thermodynamical properties of the black hole and then apply it to define a heat engine. Then, we analyze how the momentum relaxation affects the efficiency of the heat engine in the limit of high ...
arxiv +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Engineering physics of superconducting hot-electron bolometer mixers
, 2017 Superconducting hot-electron bolometers are presently the best performing mixing devices for the frequency range beyond 1.2 THz, where good quality superconductor-insulator-superconductor (SIS) devices do not exist.
Klapwijk, T. M., Semenov, A. V.
core +2 more sources
The Oblique Basis Method from an Engineering Point of View [PDF]
, 2012 The oblique basis method is reviewed from engineering point of view related to vibration and control theory. Examples are used to demonstrate and relate the oblique basis in nuclear physics to the equivalent mathematical problems in vibration theory. The
Gueorguiev, V. G.
core +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Students frequently ask: ‘Yes but...What is the utility of physics?’ [PDF]
, 2015 Two Teaching Innovation Projects were carried out in the framework of the subjects ‘Physics I’ and ‘Physics II’ for different Degrees on Engineering at the Engineering High School of the University of Cadiz, Spain, during the 2013-2014 course. The aim of
Cárdenas Leal, José Luis +6 more
core +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Investigating student understanding of heat engine: a case study of Stirling engine [PDF]
arXiv, 2020 We report on the study of student difficulties regarding heat engine in the context of Stirling cycle within upper-division undergraduate thermal physics course. An in-class test about a Stirling engine with a regenerator was taken by three classes, and the students were asked to perform one of the most basic activities---calculate the efficiency of ...
arxiv
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source