Results 51 to 60 of about 1,700,236 (333)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Quantum-Matter Heterostructures

open access: yes, 2016
Combining the power and possibilities of heterostructure engineering with the collective and emergent properties of quantum materials, quantum-matter heterostructures open a new arena of solid-state physics.
Boschker, Hans, Mannhart, Jochen
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Basic Physics Learning Process in Electrical Engineering Vocational Education Program Using Ispring Presenter Interactive Powerpoints to Improve Student Understanding [PDF]

open access: yes, 2020
The Department of Vocational Education in Electrical Engineering (JPVTE) is one of the departments based in the Faculty of FKIP UNTIRTA. The physics course at JPVTE is a fundamental concept that must be understood by the first half of students Because ...
Irwanto, I. (Irwanto)
core  

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Scanning electron microscopy of cold gases

open access: yes, 2015
Ultracold quantum gases offer unique possibilities to study interacting many-body quantum systems. Probing and manipulating such systems with ever increasing degree of control requires novel experimental techniques. Scanning electron microscopy is a high
Ott, Herwig, Santra, Bodhaditya
core   +1 more source

Dynamic analysis of a class of neutral delay model based on the Runge-Kutta algorithm

open access: yesEURASIP Journal on Wireless Communications and Networking, 2018
In this paper, we study the dynamics of a class of second-order neutral delay nonlinear models. This study is applicable to many fields, such as engineering, cybernetics, and physics.
Hongying Luo
doaj   +1 more source

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

open access: yesFEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran   +6 more
wiley   +1 more source

The continuum discretized coupled-channels method and its applications

open access: yes, 2012
This is a review on recent developments of the continuum discretized coupled-channels method (CDCC) and its applications to nuclear physics, cosmology and astrophysics, and nuclear engineering.
Matsumoto, Takuma   +3 more
core   +1 more source

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