Results 61 to 70 of about 2,429,228 (292)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Evaluating a Physics Engine as an Ingredient for Physical Reasoning [PDF]

open access: yes, 2010
Physics engines have been used in robotics research for a long time. Beside their traditional application as a substitute for real world interactions due to their higher speed, safety and flexibility, they have recently also been used for motion planning and high level action planning. We propose to further explore the idea of using a physics engine as
Weitnauer, Erik   +2 more
openaire   +3 more sources

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Industrial Engineering with Large Language Models: A case study of ChatGPT's performance on Oil & Gas problems [PDF]

open access: yesarXiv, 2023
Large Language Models (LLMs) have shown great potential in solving complex problems in various fields, including oil and gas engineering and other industrial engineering disciplines like factory automation, PLC programming etc. However, automatic identification of strong and weak solutions to fundamental physics equations governing several industrial ...
arxiv  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Microelectronics Process Engineering at San Jose State University: A Manufacturing-Oriented Interdisciplinary Degree Program [PDF]

open access: yes, 2002
San Jose State University\u27s new interdisciplinary curriculum in Microelectronics Process Engineering is described. This baccalaureate program emphasizes hands-on thin-film fabrication experience, manufacturing methods such as statistical process ...
Allen, Emily   +5 more
core   +1 more source

Jacobi Elliptic Functions and the Complete Solution to the Bead on the Hoop Problem

open access: yes, 2012
Jacobi elliptic functions are flexible functions that appear in a variety of problems in physics and engineering. We introduce and describe important features of these functions and present a physical example from classical mechanics where they appear: a
Baker, Thomas E., Bill, Andreas
core   +1 more source

Advances in Engine Efficiency: Nanomaterials, Surface Engineering, and Quantum-based Propulsion [PDF]

open access: yesarXiv, 2023
This study explores strategies to improve engine efficiency through innovative materials, design concepts, and alternative energy sources. It highlights the use of nanomaterials and surface engineering to create hydrophobic or other types of surfaces for harnessing entropy-gradient forces. Additionally, it discusses the potential of information-burning
arxiv  

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

Franck-Condon Physics in A Single Trapped Ion

open access: yes, 2011
We propose how to explore the Franck-Condon (FC) physics via a single ion confined in a spin-dependent potential, formed by the combination of a Paul trap and a magnetic field gradient.
Aji V Moore J E Varma C M   +16 more
core   +1 more source

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