Results 61 to 70 of about 1,700,236 (333)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Phase Retrieval with Application to Optical Imaging [PDF]
, 2014 This review article provides a contemporary overview of phase retrieval in optical imaging, linking the relevant optical physics to the information processing methods and algorithms.
Chapman, Henry N. +5 more
core +2 more sources
Effect of National Senior Certificate maths on the pass rate of first-year Engineering physics
South African Journal of Science, 2012 There has been much controversy about the mathematics results of the 2008 National Senior Certificate examinations - the first to be written by pupils following the outcomes-based curriculum.
Jagathesan Govender, Mervlyn Moodley
doaj
iScienceSummary: The existing infrared target simulation system with a total internal reflection (TIR) prism has the problem of low imaging contrast ratio, which will seriously affect the quality of the simulated image.
Zongyu Du +6 more
doaj +1 more source
Equitable approach to introductory calculus-based physics courses focused on problem solving
Physical Review Physics Education Research, 2022 Introductory calculus-based mechanics (“Physics 1”) is an important gateway course for students desiring to pursue a science, technology, engineering, and mathematics (STEM) career.
Eric Burkholder +4 more
doaj +1 more source
Evaluating a Physics Engine as an Ingredient for Physical Reasoning [PDF]
, 2010 Physics engines have been used in robotics research for a long time. Beside their traditional application as a substitute for real world interactions due to their higher speed, safety and flexibility, they have recently also been used for motion planning and high level action planning. We propose to further explore the idea of using a physics engine as
Weitnauer, Erik +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Computer program draws three-dimensional surfaces [PDF]
, 1972 Computer plotting program PLOT 3D draws views of surface forms z = f(x,y). Surface thus defined by program may be drawn after arbitrary rotations. Program portrays behavior of various functions involving two variables in many engineering, physics, and ...
Canright, R. B., Jr., Swigert, P.
core +1 more source
Utilizing Knowledge of Physics in Safety Engineering
Communications, 2011 Any technician working in safety engineering needs certain knowledge of physics. This knowledge includes physical quantities and units of measurement, physical properties of substances, various formulae and equations, etc.
Jiri Svec, Radomir Scurek, Pavel Svec
doaj +1 more source