Results 71 to 80 of about 1,700,236 (333)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

High-precision compensation method for the form error of a glass aspheric lens in precision glass molding

open access: yesiScience
Summary: Addressing challenges in controlling viscoelastic shrinkage-induced thermal deformation errors in precision glass molding, this article proposes a mold compensation method that combines the pre-compensation of form error prediction based on ...
Chengsong Shu   +4 more
doaj   +1 more source

Analysis of contextual teaching and learning (CTL) in the course of applied physics at the mining engineering department

open access: yesInternational Journal of Science and Applied Science: Conference Series, 2017
Applied Physics is used to comprehend any other technical engineering studies and as the foundation of technology innovation. As one of the curriculum components in helping the students to be competent in certain skills, it is used to develop ...
Fadhilah Fadhilah   +2 more
doaj   +1 more source

Textbook Of Engineering Physics

open access: yes, 2017
Chapter 1: Modern Physics Chapter 2: Quantum Mechanics Chapter 3: Electrical Conductivity in Metals Chapter 4: Dielectric and Magnetic Properties of Materials Chapter 5: Lasers Chapter 6: Optical Fibers and Superconductivity Chapter 7: Crystal Structures Chapter 8: Material ...
H. J. Ravindra, Sreeramana Aithal
openaire   +2 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Re-engineering a nanodosimetry Monte Carlo code into Geant4: software design and first results

open access: yes, 2009
A set of physics models for nanodosimetry simulation is being re-engineered for use in Geant4-based simulations. This extension of Geant4 capabilities is part of a larger scale R&D project for multi-scale simulation involving adaptable, co-working ...
Gargioni, E., Grichine, V., Pia, M. G.
core   +1 more source

Diversified approaches and strategies for developing engineering thinking among students of pedagogical universities [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Акмеология образования. Психология развития
The relevance of this research lies in the need to train highly qualifi ed specialists with engineering thinking. These specialists are crucial for developing the country’s scientifi c and technical potential.
Shefer, Olga R.   +3 more
doaj   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

On ADE Quiver Models and F-Theory Compactification

open access: yes, 2005
Based on mirror symmetry, we discuss geometric engineering of N=1 ADE quiver models from F-theory compactifications on elliptic K3 surfaces fibered over certain four-dimensional base spaces.
A Belhaj   +14 more
core   +1 more source

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