Results 131 to 140 of about 2,141,178 (305)
Di-(2-ethylhexyl) phthalate (DEHP) has become an increasingly serious pollutant in soils. Microbial degradation represents a highly promising approach for its remediation.
Wenli Zhang +5 more
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
NASA Space Engineering Research Center for utilization of local planetary resources [PDF]
In 1987, responding to widespread concerns about both the health of American space technology development and the academic preparation of 21st-century space professionals, NASA announced a nationwide competition to establish a number of Space Engineering
core +1 more source
The organization of the engineering site preparation
Пропонуються основні рішення організації інженерної підготовки будівельного майданчика з урахуванням функціональних ознак виконання робіт і систематизації однорідних ділянок по групах. Установлено залежності розподілу обсягу підготовчих робіт, дається зміна структури та обсягу робіт підготовчого періоду як функція щільності забудови.
Oleynik, P. І., Brodsky, V. I.
openaire +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
PACE 2: Pricing and Cost Estimating Handbook [PDF]
An automatic data processing system to be used for the preparation of industrial engineering type manhour and material cost estimates has been established.
Shepherd, T., Stewart, R. D.
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Space Station Furnace Facility. Volume 2: Requirements definition and conceptual design study [PDF]
The Space Station Freedom Furnace (SSFF) Project is divided into two phases: phase 1, a definition study phase, and phase 2, a design and development phase.
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
PENERAPAN WORK PREPARATION DAN INTENSITAS PENDAMPINGAN PADA CAPAIAN PRESTASI PRAKTIK PEMESINAN MAHASISWA JURUSAN MESIN FAKULTAS TEKNIK UNIVERSITAS NEGERI YOGYAKARTA [PDF]
Work Preparation and Coaching Intensity to Improve Mechanical Engineering Students’ Academic Achievement in the Machinery Practicum in the Engineering Faculty of the Yogyakarta State University.
Th. Sukardi, Dr.
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