Results 71 to 80 of about 689,327 (298)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Experimental verification and 4E analysis of a hydrate-based CO2 capture system for flue gas decarbonization

open access: yesCarbon Neutrality
Gas hydrates, crystalline compounds composed of water and guest molecules, have gained attention for their potential in selective CO₂ capture and storage.
Xiaoming Wang   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Experiment on Flotation Energy Consumption of Coal Gasification Slag with Different Particle Fineness

open access: yesKuangchan zonghe liyong
Coal gasification slag is a solid by-product produced by the coal gasification process, which has certain utilization value but is difficult to complete separation.
Ruifeng CHEN   +4 more
doaj   +1 more source

Preparing minority scientists and engineers (220.1)

open access: yesThe FASEB Journal, 2014
African Americans comprise about 14 percent of college students in the U.S. but earn only ~ 7 percent of bachelors degrees and ~3 percent of doctoral degrees in STEM fields. We have developed a system for diversifying our undergraduate and graduate STEM programs that focuses on high expectations and achievement.
Michael Summers, Freeman Hrabowski
openaire   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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