Results 61 to 70 of about 1,110,977 (259)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

New materials for micro-scale sensors and actuators:an engineering review [PDF]

, 2007
This paper provides a detailed overview of developments in transducer materials technology relating to their current and future applications in micro-scale devices.
Iosub, R, Safaa, M. Al-hilli, Rusu, Cristina, Christer Johansson, Nur, Omer,, Zhang, Q., Matovic, J, Wilson, S.A.,, Carlsson, D., Rusu, C.,, Dorey, Robert A., Djinovic, Z.,, Magnus Willander, Jager, Edwin W.H., Kohl, Manfred, Johansson, Christer,, Al-hilli, S.M., Nur, O.,, Samel, B, Wahab, Qamar Ul, Kohl, M, Matovic, J.,, Quandt, Eckhard, Willander, Magnus, Bowen, C. R., Willander, M., Persson, K, Nur, O., Kohl, M., Abad, Estefania, Zhang, Qi, Jourdain, Renaud P.J., Edwin W.H. Jager, Persson, K.,, van der Wijngaart, Wouter, Djinovic, Z., Abad, E., Johansson, Christer, Michael Wegener, Dorey, RA, Safaa, MA-H, Quandt, E.,, Rusu, C., Jourdain, R. P. J., Katrin Persson, Dorey, R. A., Michael Wendlandt, Zhang, Q, Carlsson, D, Pagounis, E., Johansson, C.,, Wegener, Michael, Rodica Iosub, Wahab, QU, Jager, Edwin, Robert A. Dorey, Wendlandt, Michael, Moldovan, C., Pagounis, E, Jager, Edwin W. H., Eckhard Quandt, Wendlandt, M., Wendlandt, M.,, Al-hilli, Safaa M., Persson, K., Iosub, R., Matovic, Jovan, Wendlandt, M, Wahab, Qamar Ul,, Moldovan, C.,, Renaud P.J. Jourdain, Djinovic, Zoran, Cristina Rusu, Qi Zhang, Safaa M. Al-hilli, Nur, Omer, van der Wijngaart, Wouter,, Matovic, J., Willander, M.,, Zhang, Q.,, Carmen Moldovan, Al-Hilli, Safaa,, Wilson, S. A., Carlsson, Daniel, Abad, E, Willander, Magnus,, Samel, B.,, Estefania Abad, Carlsson, D.,, Johansson, C, Daniel Carlsson, Johansson, C., Wilson, SA, Jourdain, R.P.-J.,, Wegener, M.,, Willander, M, van der Wijngaart, W, Samel, Bjorn, Manfred Kohl, Moldovan, C, Samel, B., Nur, O, Kohl, M.,, Pagounis, Emmanouel, Wijngaart, W. van der, Iosub, Rodica, Jager, Edwin,, Jager, E. W. H., Emmanouel Pagounis, Qamar Ul Wahab, Omer Nur, Djinovic, Z, Stephen A. Wilson, Quandt, E, Bowen, Chris R., Dorey, R.A., Jourdain, Renaud P.-J., Rusu, C, Abad, E.,, Jourdain, R.P.-J., Al-hilli, S. M., Pagounis, E.,, Wilson, S.A., Quandt, E., Wouter van der Wijngaart, Al-hilli, S.M.,, Jourdain, Renaud P. J., Ul Wahab, Q., Moldovan, Carmen, Bowen, C.R.,, Jovan Matovic, Chris R. Bowen, van, der Wijngaart W., Wegener, M, Dorey, R.A.,, van, der Wijngaart W.,, Bowen, C.R., Wegener, M., Wilson, Stephen A., Jourdain, RPJ, Persson, Katrin, Zoran Djinovic, Bowen, CR, Jager, EWH, Moldovan, Carmen; orcid:, Björn Samel, Wahab, Q.U., Safaa, M.A.H., Jager, E.W.H., Jourdain, R.P.J.   +149 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Zinc-substituted hydroxyapatite: A biomaterial with enhanced bioactivity and antibacterial properties

, 2013
10.1007/s10856-012-4817-xJournal of Materials Science: Materials in Medicine242437 ...
Aizawa, M., Lim, P.N., Thian, E.S., Kawanobe, Y., Choong, Cleo Swee Neo, Lim, P. N., Ho, B., Thian, E. S., Choong, C., Konishi, T.   +9 more
core   +1 more source

Materials Science and Engineering Baccalaureate Degree Annual Program Outcomes Assessments, 2021-22 [PDF]

, 2022
This report reviews Wright State University\u27s Materials Science and Engineering Baccalaureate Degree program for the 2021-2022 academic ...
College of Engineering and Computer Science, Wright State University
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Superconducting DC-sputtered Nb3Ge films : fabrication, structure, and properties

, 1979
Thesis (Sc.D.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 1979.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Vita.Includes bibliographical references.by James Allen Gregory.Sc ...
Gregory, James Allen
core  

Retracted: Effect of Reinforcement on Tensile Characteristics in AA 5052 with ZrC and Fly Ash-Based Composites

Advances in Materials Science and Engineering, 2023
Advances in Materials Science and Engineering
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source