Results 51 to 60 of about 1,482,915 (314)
Model-based systems engineering for life-sciences instrumentation development [PDF]
, 2018 Next‐generation genome sequencing machines and Point‐of‐Care (PoC) in vitro diagnostics devices are precursors of an emerging class of Cyber‐Physical Systems (CPS), one that harnesses biomolecular‐scale mechanisms to enable novel “wet‐technology ...
Svendsen, Winnie Edith +10 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
World Congress on Engineering 2015
, 2016 This volume presents selected peer-reviewed, revised and extended research articles written by prominent researchers who participated in the World Congress on Engineering 2015, held in London, UK, 1-3 July, 2015.
Ao, Sio-iong, Gelman, Len, Yang, Gi-Chul
core +1 more source
iScienceSummary: Chronic nonunion of bone defects remains a significant challenge in orthopedic treatment. Artificial bone graft materials are expected to solve this problem due to their suitable degradation rate and good osteoconductivity.
Haotian Zhu +10 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
iScienceSummary: Amphibious vehicles play a vital role in flood control, emergency response, and cross-terrain operations. However, most existing studies have focused on their hydrodynamic performance, while the structural vibration characteristics of amphibious
Gang Li +6 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
International meeting on applied sciences and engineering
, 2018 The goal aim objective of the 4th International Meeting on Applied Sciences and Engineering (EISI), is to promote a space for the exchange of knowledge between the academy and the industrial sector of the department of Norte de Santander, Colombia. The
V-Niño, E D +2 more
core +1 more source
Diagrammatic Models in the Engineering Sciences [PDF]
, 2008 This paper is concerned with scientific reasoning in the engineering sciences. Engineering sciences aim at explaining, predicting and describing physical phenomena occurring in technological devices. The focus of this paper is on mathematical description.
Boon, Mieke; id_orcid, Boon, Mieke
core +1 more source
iScienceSummary: Traditional apparel assembly technology—cut and sewn process—requires labor-intensive pre- and post-production. While conventional weaving technology has made efforts to streamline the garment-making process, additional assembly processes are ...
Yuyuan Shi +4 more
doaj +1 more source