Results 111 to 120 of about 1,590,550 (317)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Auto-coding UML statecharts for flight software [PDF]
, 2006 Statecharts have been used as a means to communicate behaviors in a precise manner between system engineers and software engineers. Handtranslating a statechart to code, as done on some previous space missions, introduces the possibility of errors ...
Benowitz, Ed, Clark, Ken, Watney, Garth
core
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Модернизация, инновация, развитие, 2015 A structural analysis of macroeconomic dynamics of the OECD countries andRussiain 1970–2008 has allowed to detect the main problem of Russian economy connected with the accumulated structural disproportions.
A. A. Akaev
doaj
NASA/DoD Aerospace Knowledge Diffusion Research Project. Paper 31: The information-seeking behavior of engineers [PDF]
Engineers are an extraordinarily diverse group of professionals, but an attribute common to all engineers is their use of information. Engineering can be conceptualized as an information processing system that must deal with work-related uncertainty ...
Barclay, Rebecca O. +3 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Application of Advanced Early Warning Systems with Adaptive Protection [PDF]
, 2015 This project developed and field-tested two methods of Adaptive Protection systems utilizing synchrophasor data. One method detects conditions of system stress that can lead to unintended relay operation, and initiates a supervisory signal to modify ...
Ashrafi, Frank +7 more
core
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
The Chemical Weapons Convention and the Role of Engineers and Scientists [PDF]
Kemija u Industriji, 2010 Chemical weapons, like all military technology, are associated with activities of scientists and engineers. However, chemical weapons differ from any other military technology because they were invented, and their first mass use directly developed by ...
Matoušek, J
doaj
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source