Results 121 to 130 of about 1,590,550 (317)

The Spectrum Bogie [PDF]

open access: yes
This poster, providing an overview of the Spectrum freight bogie, was presented at the Railway Engineers Forum (REF) Technical Seminar held at the Institution of Civil Engineers on the 15th June ...
Bezin, Yann   +4 more
core  

Middle school students' perceptions of engineering [PDF]

open access: yes, 2011
This paper focuses on implementing engineering education in middle school classrooms (grade levels 7-9). One of the aims of the study was to foster students’ and teachers’ knowledge and understanding of engineering in society.
Dawes, Les, English, Lyn, Hudson, Peter
core   +1 more source

Engineering without engines

open access: yes, 2017
El Trabajo Fin de Grado se plantea como un ejercicio de investigación sobre cómo afectan hoy en día las tecnologías a la sostenibilidad en la arquitectura a través de una serie de proyectos que incorporan la vanguardia tecnológica en el proceso de diseño de los edificios con un enfoque sostenible.
Rodríguez Gil, Nuria   +2 more
openaire   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Editorial

open access: yesJournal of Energy in Southern Africa
Artificial intelligence could revolutionise the education and training of the next generation of power and energy engineers and researchers.
Komla A Folly
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 13: The information-seeking habits and practices of engineers [PDF]

open access: yes
It is argued that only by maximizing the research and development process can the United States maintain and possibly capture its international competitive edge.
Pinelli, Thomas E.
core   +1 more source

Development of a Collaborative, Distance Learning Based route to BEng/MEng qualification for Engineers in Employment. [PDF]

open access: yes, 2010
This report presents the development of an integrated programme entitled MEng Engineering that will provide an opportunity for engineers already in the workforce to engage with upskilling that can lead to their gaining professional recognition ...
Humphries-Smith, Tania
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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