Results 181 to 190 of about 4,806,683 (407)
, 2013 This essay describes Jack\u27s experience dealing with World Cup fever in Bath, England, during the 2010 World Cup. It\u27s Jack\u27s outsider\u27s perspective on the impact of world cup competition while he taught in the Advanced Studies in England ...
Ryan, Jack
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Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings
Advanced Materials, EarlyView.Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed +9 more
wiley +1 more source
What’s Wrong with McCloskey on the Earth Charter [PDF]
This note responds to Deirdre McCloskey's 2002 critique of the Earth Charter by arguing that the concepts of sustainability, intergenerational equity and political democracy are essential to an understanding of that international manifesto.
Richard W. England
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Advanced Materials, EarlyView.Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park +15 more
wiley +1 more source
Budget crises in the six New England states have prompted spending cuts, leaving taxpayers to ask, "Where does the state spend our money?"State finance - New England ; Fiscal policy - New ...
E. Matthew Quigley
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Advanced Materials Technologies, EarlyView.The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon +6 more
wiley +1 more source
Advanced Science, EarlyView.Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater +13 more
wiley +1 more source
Mental health crisis resolution teams and crisis care systems in England: a national survey [PDF]
, 2018 Brynmor Lloyd‐Evans +5 more
openalex +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source