Results 261 to 270 of about 4,566,700 (407)
Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells
Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng+14 more
wiley +1 more source
XXIII. On a new Species of Wild Swan, taken in England, and hitherto confounded with the Hooper. [PDF]
William Yarrell
openalex +1 more source
Hemiptera Collected in Western New England, Chiefly From Mountains [PDF]
H. M. Parshley
openalex +1 more source
Advanced Cancer Immunotherapy via SMARCAL1 Blockade Using a Glucose‐Responsive CRISPR Nanovaccine
A glucose‐catalyzed chemodynamic strategy is proposed to activate therapeutic genome editing of SMARCAL1to improve cancer immunotherapy. This innovative design featuring Fenton reaction activity and glucose consumption ability, not only effectively synergizes to activate the cGAS‐STING pathway but also inhibits the opposing functions of interferon by ...
Yuwei Li+8 more
wiley +1 more source
Spatial distribution of Culex mosquitoes across England and Wales, July 2023. [PDF]
Widlake E+21 more
europepmc +1 more source
The Taxonomic Value of the Ovipositor in the New England Species of the Genus Corythucha Stål (Hemiptera: Tingidae) [PDF]
Albert Edward Feldman, Norman S. Bailey
openalex +1 more source
This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado+10 more
wiley +1 more source
Smoking prevalence and purchasing of menthol cigarettes since the menthol flavour ban in Great Britain: a population-based survey between 2020 and 2023. [PDF]
Buss VH+5 more
europepmc +1 more source