Results 51 to 60 of about 1,080,903 (314)
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
Left behind: reflections of residential care home managers when children leave
Scottish Journal of Residential Child Care, 2021 A case study of a children's therapeutic residential care provider consisting of five homes in England was carried out to consider the feelings and reflections of the managers on children leaving the home. This is an unexplored perspective/ subject which
Yesha Bhagat, Barbara O'Reilly
doaj +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Representation of power of first Tudors in new political history
Вестник Мининского университета, 2017 The article discusses the possibility of studying the representation of the royal power of the first Tudors period in England in line with one of the fastest growing areas of historical science - the new political history.
D. V. Kiryukhin
doaj +2 more sources
One Health, One National Park: A Contribution to New Perspectives and Economics for Modern Times
Wieś i Rolnictwo, 2020 One Health is a concept that sees human, animal, and environmental health as parts of a single interdependent system. The Covid-19 pandemic, its implications reaching far beyond the direct effects of a coronavirus on people’s health, underlines the ...
Keith S. Howe
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Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
The perception of “insular” England in “insular” Japan
Японские исследованияThe insular position has serious influence on history and mentality. However, this provision “works” only in conjunction with other factors. Japan and England are island nations, but the history of England is characterized by the maximum number of ...
A. N. Meshcheryakov
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Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
1851 LONDRA SERGİSİ VE OSMANLI DEVLETİ’NİN KATILIŞI
Akademik İncelemeler Dergisi, 2018 Sanayi devrimi sonrası Avrupa Devletleri’nde üretimin artması, yeni pazar ve hammadde ihtiyacını da beraberinde getirmiştir. Bu ihtiyacın giderilebilmesi için sanayi ürünlerinin ve üretim araçlarının tanıtılması amacı ile uluslararası sergiler ...
Aziz Tekdemir
doaj +1 more source