Results 221 to 230 of about 120,140,799 (291)

Neuroprotective effects of quercetin in animal models of neurodegenerative diseases: A systematic review and meta‐analysis

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho   +6 more
wiley   +1 more source

Mechanism of RNA‐Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu   +2 more
wiley   +1 more source

Invention of the Flexible Fiberoptic Nasopharyngolaryngoscope: Perspectives From the East

open access: yesThe Laryngoscope, EarlyView.
The fiberoptic nasopharyngolaryngoscope was developed in 1967 by Drs. Masayuki Sawashima, Hajime Hirose, and Osamu Fujimura at the University of Tokyo's Research Institute of Logopedics and Phoniatrics (RILP), building on Dr. Shigeto Ikeda's 1962 fiberoptic bronchoscope during Japan's postwar surge in technological innovation.
Carolyn J. Khoury   +7 more
wiley   +1 more source

Guidelines for Meta‐Analytic Structural Equation Modeling: Steps, Resources, and Illustrations

open access: yesPsychology &Marketing, EarlyView.
ABSTRACT The goal of science is to build incremental, structured, and reliable knowledge over time. Yet, many strands of marketing and related disciplines exhibit symptoms of cumulative stagnation, including lack of replicability and weak theoretical integration. Existing remedies such as replication studies, multistudy investigations, and open science
Hassam Waheed, Weng Marc Lim
wiley   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

open access: yesMovement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska   +6 more
wiley   +1 more source

Looking backward to move forward: Enhancing metadata in scientific collections through interdisciplinary collaboration

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Early modern herbaria house important and useful data on historic environments. However, their contents are often inhospitable to scientific use. Despite this challenge, once their contents have been deciphered, such specimens present novel research opportunities.
Madeline E. White, Stephen A. Harris
wiley   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

open access: yesPhytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li   +4 more
wiley   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

open access: yesRheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues   +6 more
wiley   +1 more source

Indoor UAV for Nuclear Investigation: Experimental Qualification and Field Feedback

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Indoor Unmanned Aerial Vehicles (UAVs) have recently gained interest for inspection and investigation tasks in hazardous environments. In the nuclear field, indoor UAVs offer promising capabilities to reduce workers' exposure to ionizing radiation while accessing confined or elevated areas.
Jérémy Seyssaud   +6 more
wiley   +1 more source

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